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病例报告:超声辅助导管定向溶栓治疗肠系膜上动脉栓塞性部分闭塞

Case report: ultrasound assisted catheter directed thrombolysis of an embolic partial occlusion of the superior mesenteric artery.

作者信息

Bongiovanni Simone, Bozzolo Marco, Amabile Simone, Peano Enrico, Balderi Alberto

机构信息

Interventional Radiology Unit, Department of Radiology, A.O. S. Croce e Carle - Cuneo, Cuneo, Italy.

Postgraduate School in Radiology, University of Turin, Turin, Italy.

出版信息

Front Radiol. 2023 May 18;3:1167901. doi: 10.3389/fradi.2023.1167901. eCollection 2023.

Abstract

Acute mesenteric ischemia (AMI) is a severe medical condition defined by insufficient vascular supply to the small bowel through mesenteric vessels, resulting in necrosis and eventual gangrene of bowel walls. We present the case of a 64-year-old man with recrudescence of prolonged epigastric pain at rest of few hours duration, cold sweating and episodes of vomiting. A computed tomography scan of his abdomen revealed multiple filling defects in the mid-distal part of the superior mesenteric artery (SMA) and the proximal part of jejunal branches, associated with small intestine walls thickening, suggesting SMA thromboembolism and initial intestinal ischemia. Considering the absence of signs of peritonitis at the abdominal examination and the presence of multiple arterial emboli was decided to perform an endovascular treatment with ultrasound assisted catheter-directed thrombolysis with EkoSonic Endovascular System-EKOS, which resulted in complete dissolution of the multiple emboli and improved blood flow into the intestine wall. The day after the procedure the patient's pain improved significantly and 5 days after he was discharged home asymptomatic on warfarin anticoagulation. After 1 year of follow-up the patient is fine with no further episodes of mesenteric ischemia or other embolisms.

摘要

急性肠系膜缺血(AMI)是一种严重的病症,定义为通过肠系膜血管向小肠供血不足,导致肠壁坏死并最终坏疽。我们报告一例64岁男性病例,患者在静息状态下出现持续数小时的上腹部疼痛复发、冷汗和呕吐发作。其腹部计算机断层扫描显示肠系膜上动脉(SMA)中远端和空肠分支近端有多个充盈缺损,伴有小肠壁增厚,提示SMA血栓栓塞和初期肠缺血。考虑到腹部检查未发现腹膜炎体征且存在多个动脉栓子,决定使用EkoSonic血管内系统-EKOS进行超声辅助导管定向溶栓的血管内治疗,结果多个栓子完全溶解,肠壁血流改善。术后第二天患者疼痛明显改善,5天后出院,服用华法林抗凝,无症状。随访1年后,患者情况良好,未再发生肠系膜缺血或其他栓塞事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5974/10365118/8f99198b32d4/fradi-03-1167901-g001.jpg

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