Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria.
Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria.
Expert Rev Hematol. 2023 Jul-Dec;16(9):659-670. doi: 10.1080/17474086.2023.2232545. Epub 2023 Jul 27.
The Vienna Cancer Stem Cell Club (VCSCC) was launched by a group of scientists in Vienna in 2002.
Major aims of the VCSCC are to support research on cancer stem cells (CSC) in hematopoietic malignancies and to translate CSC-related markers and targets into clinical application. A primary focus of research in the VCSCC is the leukemic stem cell (LSC). Between 2013 and 2021, members of the VCSCC established a special research program on myeloproliferative neoplasms and since 2008, members of the VCSCC run the Ludwig Boltzmann Institute for Hematology and Oncology. In all these years, the VCSCC provided a robust intellectual platform for translational hematology and LSC research in Vienna. Furthermore, the VCSCC interacts with several national and international study groups and societies in the field. Representatives of the VCSCC also organized a number of international meetings and conferences on neoplastic stem cells, including LSC, in the past 15 years, and contributed to the definition and classification of CSC/LSC and related pre-malignant and malignant conditions.
The VCSCC will continue to advance the field and to develop LSC-detecting and LSC-eradicating concepts through which diagnosis, prognostication, and therapy of blood cancer patients should improve.
维也纳癌症干细胞俱乐部（VCSCC）由 2002 年维也纳的一群科学家成立。
VCSCC 的主要目标是支持造血恶性肿瘤中癌症干细胞（CSC）的研究，并将 CSC 相关标志物和靶点转化为临床应用。VCSCC 的研究重点之一是白血病干细胞（LSC）。在 2013 年至 2021 年期间，VCSCC 的成员建立了一个关于骨髓增殖性肿瘤的特别研究计划，自 2008 年以来，VCSCC 的成员一直在运营路德维希·博尔茨曼血液学和肿瘤学研究所。在所有这些年里，VCSCC 为维也纳的转化血液学和 LSC 研究提供了一个强大的知识平台。此外，VCSCC 还与该领域的几个国家和国际研究小组和学会进行互动。VCSCC 的代表还在过去 15 年组织了多次关于肿瘤干细胞（包括 LSC）的国际会议和研讨会，并为 CSC/LSC 及相关前恶性和恶性疾病的定义和分类做出了贡献。
VCSCC 将继续推进该领域的发展，并通过开发 LSC 检测和 LSC 消除的概念，改善血液癌症患者的诊断、预后和治疗。
