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肺部和胸膜的自身免疫性疾病(作者译)

[Autoimmune diseases in the lungs and pleura (author's transl)].

作者信息

Ferlinz R

出版信息

Prax Klin Pneumol. 1979 Apr;33 Suppl 1:323-32.

PMID:37494
Abstract

Diseases of autoaggression can be produced if immunotolerance to endogenous tissue is lost. Such diseases become manifest in the pulmonary and pleura regions mainly within the framework of systemic diseases of the connective tissue (collagenoses) and of the vessels (angiitides). Lupus erythematodes disseminatus belongs to the first group which also includes rheumatoid arthritis, sclerodermia, and dermatomyositis, whereas panarteritis nodosa belongs to the second group, which comprises among others arteritis of the arteria pulmonalis, Wegener's granulomatosis, Goodpasture's syndrome and Ceelen's disease. Pleuropulmonary involvement is frequent in these systemic diseases; it is in fact the principal sign in Goodpasture's syndrome and in Ceelen's disease.

摘要

如果对内源性组织的免疫耐受性丧失,就可能引发自身攻击性疾病。这类疾病主要在结缔组织(胶原病)和血管(血管炎)的全身性疾病范围内,在肺部和胸膜区域表现出来。播散性红斑狼疮属于第一组疾病,该组还包括类风湿性关节炎、硬皮病和皮肌炎,而结节性多动脉炎属于第二组疾病,该组尤其包括肺动脉炎、韦格纳肉芽肿病、古德帕斯彻综合征和塞伦病。胸膜肺部受累在这些全身性疾病中很常见;事实上,它是古德帕斯彻综合征和塞伦病的主要症状。

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