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[通过计算机模拟研究决定受辐照细胞克隆形成能力的因素]

[Study of factors determining the clonogenic capacity of irradiated cells by computer simulation].

作者信息

Danielian S A, Zorin A V, Iakovlev A Iu

出版信息

Radiobiologiia. 1986 Jul-Aug;26(4):516-20.

PMID:3749475
Abstract

The methods of the multifactor disperse analysis of the results of studies of the simulation model of the effect of ionizing radiation on cell populations were used to study the role of some characteristics of the stationary culture in its response to a single radiation effect. The clonogenic capacity of cells was used as a criterion for assessing the biological effect of radiation. "The share of resting cells" was a predominant factor influencing the survival of irradiated cell populations.

摘要

采用对电离辐射作用于细胞群体的模拟模型研究结果进行多因素离散分析的方法,来研究静止培养物的某些特性在其对单次辐射效应的反应中的作用。细胞的克隆形成能力被用作评估辐射生物学效应的标准。“静止细胞的比例”是影响受辐照细胞群体存活的主要因素。

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