Beijing Haidian District Maternal and Child Health Care Hospital, Beijing, China.
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China.
Sci Total Environ. 2023 Nov 15;899:165713. doi: 10.1016/j.scitotenv.2023.165713. Epub 2023 Jul 24.
Previous studies have proved that exposure to extreme temperature in specific windows of pregnancy could cause some complications, such as pregnancy induced hypertension (PIH) and gestational diabetes mellitus (GDM), but differences in the effect of extreme temperature on the 2 complications are rarely studied. We carried a retrospective study on the impact of temperature on GDM/PIH in different trimesters based on data from a maternal and child health center in Beijing, China. Ambient temperatures (°C) were obtained from the China Meteorological Administration from January 1st, 2013 to May 15th, 2018. We use distributed lag non-linear models (DLNMs) combined with logistic regression to calculate the lag exposure-response relationships between the temperature and GDM/PIH from 1st to 24th/20th weeks of pregnancy. In both first and second trimesters, the risk of GDM was increased in summer with high temperatures; in second trimester, the risk of GDM increased in winter with low temperatures. In first half of pregnancy, risk of PIH was decreased in winter with low temperatures. These findings can provide the guideline for preventing the GDM and PIH induced by extreme temperature during pregnancy.
先前的研究已经证明，在妊娠特定窗口期暴露于极端温度会导致一些并发症，如妊娠高血压（PIH）和妊娠糖尿病（GDM），但极端温度对这两种并发症的影响差异很少被研究。我们基于中国北京一家妇幼保健中心的数据，进行了一项关于温度对不同孕期 GDM/PIH 影响的回顾性研究。环境温度（°C）来自中国气象局，时间为 2013 年 1 月 1 日至 2018 年 5 月 15 日。我们使用分布式滞后非线性模型（DLNMs）结合逻辑回归，计算了妊娠第 1 周到第 24 周/第 20 周期间温度与 GDM/PIH 之间的滞后暴露-反应关系。在第一和第二孕期，夏季高温时 GDM 的风险增加；在第二孕期，冬季低温时 GDM 的风险增加。在妊娠前半段，冬季低温时 PIH 的风险降低。这些发现可为预防妊娠期间极端温度引起的 GDM 和 PIH 提供指导。
