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原发性干燥综合征的亚急性进行性听力损失和下半身帕金森病。

Subacute Progressive Hearing Loss and Lower Body Parkinsonism in Primary Sjögren's Syndrome.

机构信息

Department of Neurology, Juntendo University Shizuoka Hospital, Japan.

Department of Neurology, Juntendo University School of Medicine, Japan.

出版信息

Intern Med. 2024 Mar 15;63(6):853-856. doi: 10.2169/internalmedicine.2158-23. Epub 2023 Jul 26.

Abstract

In primary Sjögren's syndrome, it is extremely rare to observe subacute progressive lower-body parkinsonism with severe sensory hearing loss responsive to corticosteroid therapy. Sjögren's syndrome can cause heterogeneous symptoms; therefore, its diagnosis and introduction of treatment are prone to be delayed, particularly in cases without sicca symptoms or seronegative cases, which are more likely to be seen in patients with neurological complications. This report may help clinicians identify atypical early neurological symptoms in primary Sjögren's syndrome.

摘要

在原发性干燥综合征中,观察到亚急性进行性下半身帕金森病伴严重感觉神经性听力损失,对皮质类固醇治疗有反应的情况极为罕见。干燥综合征可引起多种不同的症状;因此,其诊断和治疗的引入容易被延迟,特别是在没有干燥症状或血清阴性的情况下,在有神经并发症的患者中更常见。本报告可能有助于临床医生识别原发性干燥综合征中的非典型早期神经症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07eb/11009000/3589d8400a43/1349-7235-63-0853-g001.jpg

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