急性肾损伤致教皇死亡的主要原因分析（1277-2005 年）：21 例病例回顾
Acute Kidney Injury as a Leading Cause of Papal Deaths in the Years 1277 to 2005: A Review of 21 Cases.
机构信息
From the Professore Emerito Università della Campania Luigi Vanvitelli, Naples, Italy.
出版信息
Exp Clin Transplant. 2023 Jun;21(Suppl 2):87-90. doi: 10.6002/ect.IAHNCongress.20.
OBJECTIVES
This study was devised to investigate papal deaths due to acute kidney injury, a topic for which scarce data exist.
MATERIALS AND METHODS
We studied all popes between John XXI, who died in 1277 of crush syndrome, and John Paul II, who died of anuria and urinary sepsis in 2005.
RESULTS
Between pontification years from 1277 to 2005, 21 of 78 popes (26.9%) died of acute kidney injury. Sepsis was identified as the leading cause of acute kidney injury and death in 20 of 21 popes (95.2%). Mean ± SE age at death of the 21 popes was 69.4 ± 2.26 years. Six popes (28.6%) died of stroke.
CONCLUSIONS
Sepsis-associated acute kidney injury, a syndrome with a complex pathogenesis and poor prognosis, which is far from being fully understood, contributed to a high number of papal deaths.
目的
本研究旨在探讨急性肾损伤导致的教皇死亡，这是一个数据稀缺的话题。
材料和方法
我们研究了自约翰二十一世（1277 年死于挤压综合征）至约翰·保罗二世（2005 年死于无尿和尿败血症）期间的所有教皇。
结果
在 1277 年至 2005 年的教皇任职期间，78 位教皇中有 21 位（26.9%）死于急性肾损伤。败血症被确定为 21 位教皇（95.2%）中急性肾损伤和死亡的主要原因。21 位教皇的平均死亡年龄为 69.4 ± 2.26 岁。6 位教皇（28.6%）死于中风。
结论
与败血症相关的急性肾损伤是一种发病机制复杂、预后不良的综合征，目前远未被充分理解，这导致了大量教皇的死亡。
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