最佳 MoCA 截断值用于筛查中国老年人轻度认知障碍：系统评价和荟萃分析。
Optimal cut-off MoCA score for screening for mild cognitive impairment in elderly individuals in China: A systematic review and meta-analysis.
机构信息
International Medical Services, Peking Union Medical College Hospital, Beijing, China.
School of Nursing, Suzhou Vocational Health College, Suzhou, China.
出版信息
Asian J Psychiatr. 2023 Sep;87:103691. doi: 10.1016/j.ajp.2023.103691. Epub 2023 Jul 14.
AIM
To evaluate the optimal cut-off MoCA score for elderly individuals with MCI.
DESIGN
A systematic review and meta-analysis.
METHOD
Articles were retrieved from PubMed, Ovid, Embase, The Cochrane Library, PsycINFO, CBM, CNKI, WanFang and CQVIP and were assessed by using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). Figures of the assessment were made by using Review Manager 5.3, and a meta-analysis of the data was conducted by using Bivariate Random-effects Meta-Analysis (BRMA) via Stata 14.0.
RESULTS
Seventeen articles were retrieved from the database, and when the cut-offs were 24/25 and 25/26, they represented the same diagnostic value; in addition, the AUC was 0.96, which demonstrated high predictive validity for mild cognitive impairment screening. However, the sensitivity was higher with 25/26 (se=0.95, sp=0.80), whereas the specificity was higher with 24/25 (se=0.92, sp=0.89).
目的
评估最佳 MoCA 截断值用于诊断轻中度认知障碍（MCI）的老年患者。
设计
系统评价和荟萃分析。
方法
检索 PubMed、Ovid、Embase、The Cochrane Library、PsycINFO、CBM、CNKI、WanFang 和 CQVIP 数据库中的相关文献，使用诊断准确性研究质量评估工具 2 版（QUADAS-2）进行文献质量评估。使用 Review Manager 5.3 软件制作评估图，采用 Stata 14.0 软件的双变量随机效应荟萃分析（BRMA）进行数据分析。
结果
从数据库中检索到 17 篇文献，当截断值为 24/25 和 25/26 时，其具有相同的诊断价值；此外，AUC 为 0.96，表明其对轻度认知障碍筛查具有较高的预测价值。然而，25/26 时的敏感度更高（se=0.95，sp=0.80），而 24/25 时的特异度更高（se=0.92，sp=0.89）。
Zotero 插件