Clinica Medica, Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Hypertens Res. 2023 Oct;46(10):2318-2325. doi: 10.1038/s41440-023-01394-9. Epub 2023 Jul 27.
Epidemiological studies have unequivocally shown that elevated heart rate values measured at rest have an adverse prognostic impact in the hypertensive patient, being associated with an increased risk of cardiovascular events and complications. In recent years new data have been collected on this issue, strengthening the clinical relevance of elevated heart rate as a specific hypertensive phenotype. The present paper will review old and new data on the prognostic importance of resting tachycardia in the hypertensive patient. It will also examine the role of the sympathetic nervous system in the development of this alteration as well as its therapeutic implications. The different approaches to dynamically assess heart rate values in the clinical setting will be finally discussed.
流行病学研究明确表明，高血压患者静息时心率升高与心血管事件和并发症风险增加相关，具有不良预后影响。近年来，这一问题有了新的数据支持，进一步证实了心率升高作为一种特定的高血压表型具有重要的临床意义。本文将回顾高血压患者静息性心动过速的预后重要性的旧有和新数据，并探讨交感神经系统在这种改变发展中的作用及其治疗意义。最后还将讨论在临床环境中动态评估心率值的不同方法。
