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奥克兰城市医院心脏手术后新发心房颤动的发生率及预测因素。

Incidence and predictors of new-onset atrial fibrillation after cardiac surgery at Auckland City Hospital.

机构信息

Clinical Nurse Specialist, Adult Cardiology, Te Whatu Ora Te Toka Tumai, Auckland, New Zealand.

School of Nursing, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

出版信息

N Z Med J. 2023 Jul 21;136(1579):13-23. doi: 10.26635/6965.6102.

DOI:10.26635/6965.6102
PMID:37501241
Abstract

AIM

To describe the incidence, ethnic differences in incidence, and predictors of post-operative atrial fibrillation (POAF) after cardiac surgery in a New Zealand hospital.

METHOD

Analysis of registry data on 1,630 adults without previous atrial fibrillation having coronary artery bypass grafting and/or valve surgery was used to determine the incidence of POAF. Univariate analysis identified risk factors and stepwise logistic regression was used to create the most parsimonious model to predict POAF.

RESULTS

Overall POAF incidence was 29% (n=465) and differed by surgery type (25% after isolated coronary artery bypass surgery (CABG) vs 42% after combined CABG+valve). Incidence was highest in Māori (35%) and NZ/Other Europeans (32%). Māori and Pasifika with POAF were on average ten years younger than NZ/Other Europeans. Independent risk factors were age (OR 1.05, 95%CI 1.04-1.06), body mass index (OR 1.04, 95%CI 1.02-1.06), history of heart failure (OR 2.08, 95%CI 1.47-2.95), and valve surgeries (isolated valve OR 1.51, 95%CI 1.16-1.95; CABG+valve OR 1.59, 95%CI 1.11-2.28), but the model had poor discrimination (AUC 0.67).

CONCLUSION

POAF in a New Zealand hospital occurs at comparable rates to international settings. Risk models using routinely measured factors offer poor predictive accuracy, meaning risk stratification is unlikely to adequately inform targeted POAF prevention in clinical practice.

摘要

目的

描述新西兰一家医院心脏手术后心房颤动(POAF)的发生率、发生率的种族差异和预测因素。

方法

分析了 1630 名无先前心房颤动的成年人的登记数据,这些成年人接受了冠状动脉旁路移植术和/或瓣膜手术,以确定 POAF 的发生率。单因素分析确定了风险因素,并逐步逻辑回归用于创建最简约的模型来预测 POAF。

结果

总体 POAF 发生率为 29%(n=465),手术类型不同(单纯冠状动脉旁路手术(CABG)后发生率为 25%,CABG+瓣膜手术后发生率为 42%)。毛利人(35%)和太平洋岛民(32%)的发生率最高。患有 POAF 的毛利人和太平洋岛民比新西兰/其他欧洲人平均年轻十岁。独立的风险因素包括年龄(OR 1.05,95%CI 1.04-1.06)、体重指数(OR 1.04,95%CI 1.02-1.06)、心力衰竭史(OR 2.08,95%CI 1.47-2.95)和瓣膜手术(单纯瓣膜 OR 1.51,95%CI 1.16-1.95;CABG+瓣膜 OR 1.59,95%CI 1.11-2.28),但该模型的判别能力较差(AUC 0.67)。

结论

新西兰医院的 POAF 发生率与国际水平相当。使用常规测量因素的风险模型提供的预测准确性较差,这意味着风险分层不太可能在临床实践中充分告知针对 POAF 的预防措施。

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