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军人航空人员中的代谢综合征、血脂异常及相关临床标志物。

Metabolic Syndrome, Hyperlipidemias, and Associated Clinical Markers Among Military Airmen.

出版信息

Aerosp Med Hum Perform. 2023 Aug 1;94(8):604-609. doi: 10.3357/AMHP.6242.2023.

Abstract

Due to the increased overweight and obesity prevalence in Colombia, the aim of this study is to determine the frequency of metabolic syndrome (MetS) among Colombian Air Force military aviators, crews, remote piloted aircraft operators, and air traffic controllers and relationships with clinical markers. Operationally active Columbian Air Force military personnel examined periodically at the Colombian Air Force Aerospace Medical Directorate were chosen for a cross-sectional study performed among 2179 subjects. Medical history, anthropometrics, and laboratory results were analyzed and frequencies, correlations, and odds ratios were calculated. Overall prevalence of MetS was 21.7%; in subjects with BMI ≥25, frequency increased to 36% vs. those with BMI <25. Hypertriglyceridemia was present in 31%, impaired fasting glucose 12.5%, hypertension (≥130/85 mmHg) 14.4%, low HDL-C 35.2%, and increased waist circumference 46.2%. Those with three criteria were 14.6%, four criteria 5.8%, and five criteria 1.2%. Pilots had a significantly lower prevalence of MetS at 17.7% and an adjusted OR of 0.61 (0.49-0.76) than other crew; hyperuricemia was three times more likely (3.2-5.1) and hypercholesterolemia OR was 2.3 (1.9-2.9). Subjects with MetS had a significantly higher fat percentage, waist circumference, low-density lipoprotein, very low-density lipoprotein, non-high-density lipoprotein cholesterol, atherogenic index of plasma (AIP), uric acid, and white blood cell (leukocyte) count, and a lower estimated glomerular filtration rate. There is a linear relationship of the AIP and waist circumference, BMI, uric acid, and white blood cell count. MetS prevalence among Colombian Air Force aviators is lower than the general population, higher than other countries, and displays worse lipid profiles that increase cardiovascular and diabetes mellitus risk within the military.

摘要

由于超重和肥胖在哥伦比亚的流行率不断增加,本研究旨在确定哥伦比亚空军军事飞行员、机组人员、远程驾驶飞机操作员和空中交通管制员中代谢综合征(MetS)的频率,并研究其与临床标志物的关系。在哥伦比亚空军航空医学主任办公室定期接受检查的现役哥伦比亚空军军人被选为横断面研究对象,共纳入 2179 名受试者。分析了受试者的病史、人体测量学和实验室结果,并计算了频率、相关性和优势比。总体 MetS 患病率为 21.7%;在 BMI≥25 的受试者中,患病率增加至 36%,而 BMI<25 的受试者中患病率为 18.6%。31%的受试者存在高三酰甘油血症,12.5%的受试者存在空腹血糖受损,14.4%的受试者存在高血压(≥130/85mmHg),35.2%的受试者存在低 HDL-C,46.2%的受试者存在腰围增大。有三项标准的占 14.6%,四项标准的占 5.8%,五项标准的占 1.2%。飞行员的 MetS 患病率明显较低,为 17.7%,调整后的优势比为 0.61(0.49-0.76),低于其他机组人员;高尿酸血症的可能性增加了三倍(3.2-5.1),高胆固醇血症的 OR 为 2.3(1.9-2.9)。患有 MetS 的受试者的体脂百分比、腰围、低密度脂蛋白、极低密度脂蛋白、非高密度脂蛋白胆固醇、血浆致动脉粥样硬化指数(AIP)、尿酸和白细胞计数明显较高,而估算的肾小球滤过率明显较低。AIP 与腰围、BMI、尿酸和白细胞计数呈线性关系。哥伦比亚空军飞行员的 MetS 患病率低于普通人群,高于其他国家,且血脂状况更差,这会增加军队中心血管疾病和糖尿病的风险。

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