Department of Orthopedic Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.
Medical Device and Robot Institute, Kyungpook National University, Daegu, Korea.
J Hand Surg Asian Pac Vol. 2023 Jun;28(3):377-381. doi: 10.1142/S2424835523500455. Epub 2023 Jul 24.
The human hand is a specialised organ for fine motion and sensation and has a relatively large representation in the homunculus. The pathway of sensation starts from information sent by mechanoreceptors in the hand. This study reports the topography of the Pacinian corpuscle in the fingertips of a human cadaver. All 10 digits from both hands of a fresh-frozen cadaver were examined. Glabrous skin distal to the distal interphalangeal joint was harvested superficial to the periosteum including fat and subcutaneous tissue. The glabrous skin were divided into 10 sections that included five distal and five proximal sections. Modified gold chloride staining was performed. Sectioned specimens were observed under a light microscope and the density of Pacinian corpuscles was determined in each segment. The density of the corpuscles was compared between the radial/ulnar and proximal/distal segments and also between digits from the right hand versus those from the left hand. Pacinian corpuscles were observed only in the subcutaneous tissue. There was no significant difference in density of the corpuscles between the distal and proximal segments or between the right and left hands. There was a statistically significant greater density of Pacinian corpuscles on the radial segments of all digits except the thumb. There is a greater density of Pacinian corpuscles on the radial side of the human fingertip in all digits except the thumb.
人手是精细运动和感觉的专门器官，在人体小人中占有相对较大的代表区域。感觉途径始于手部机械感受器发送的信息。本研究报告了人类尸体指尖处Pacinian 小体的分布情况。对一具新鲜冷冻尸体的双手的所有 10 个手指进行了检查。在骨膜浅层采集远节指间关节远端的无毛发皮肤，包括脂肪和皮下组织。无毛发皮肤被分为 10 个部分，包括 5 个远侧部分和 5 个近侧部分。进行了改良的氯化金染色。对切片标本进行了在光显微镜下观察，并确定了每个节段Pacinian 小体的密度。比较了近侧/远侧节段和右手与左手之间的小体密度。Pacinian 小体仅存在于皮下组织中。在近侧和远侧节段之间或右手和左手之间，小体的密度没有差异。除拇指外，所有手指的桡侧节段Pacinian 小体的密度都有统计学意义上的增加。除拇指外，人类指尖的桡侧各指Pacinian 小体的密度都较高。
