Kim Ji Hyun, Park Channy, Yang Xiaopeng, Murakami Gen, Abe Hiroshi, Shibata Shunichi
Department of Anatomy, Seonam University College of Medicine, Namwon, Korea.
Department of Physiology, Seonam University College of Medicine, Namwon, Korea.
Anat Rec (Hoboken). 2018 Jan;301(1):154-165. doi: 10.1002/ar.23707. Epub 2017 Nov 4.
The detailed distribution of Pacinian corpuscles was evaluated by viewing the transverse sections of all fingers and thumbs, including the interdigital areas, from eight hands of five fetuses of gestational age 28-33 weeks (crown-rump length 230-290 mm). Among the 40 fingers and thumbs, serial sections were prepared for 3D reconstructions of nerve elements in the distal and middle phalangeal segments of three fifth fingers; in these three fingers, the distal segment contained 45-75 Pacinian corpuscles. These Pacinian corpuscles were 0.2-1.0 mm in length and 0.05-0.3 mm in thickness, oriented along the proximodistal axis and arranged along the palmar digital nerve branches. Other than beneath the digital skin, small corpuscles (<0.1 mm in thickness) were observed within the tendon sheath of the flexors in the middle or distal segment of five fetuses and in the nail beds of four fetuses. Clusters of 5-20 corpuscles formed bouquet- or tree-like arrangements along neurovascular bundles in the fingers, thumbs and interdigital areas. Because the space beneath the skin was thick and loose in the interdigital area, trees in the interdigital area were up to 2 mm long. Regardless of site, the central core of each corpuscle was positive for S100 protein, while the core and parts of the capillaries in the corpuscle were weakly positive for nestin. Because corpuscles in the tendon sheath and nail bed, as well as bouquet- and tree-like arrangements of corpuscles, have not been reported in adults, these morphologies are likely specific to fetuses. Anat Rec, 2017. © 2017 Wiley Periodicals, Inc. Anat Rec, 301:154-165, 2018. © 2017 Wiley Periodicals, Inc.
通过观察28 - 33周胎龄（顶臀长230 - 290毫米）的5个胎儿的8只手的所有手指和拇指（包括指间区域）的横切面，评估了环层小体的详细分布。在40根手指和拇指中，对三根第五指的远节和中节指骨段的神经元件进行了三维重建的连续切片制备；在这三根手指中，远节段含有45 - 75个环层小体。这些环层小体长度为0.2 - 1.0毫米，厚度为0.05 - 0.3毫米，沿近远轴排列，并沿着指掌侧神经分支分布。除了指皮肤下方，在5个胎儿的中节或远节段屈肌腱鞘内以及4个胎儿的甲床内观察到了小的小体（厚度<0.1毫米）。5 - 20个小体的簇沿着手指、拇指和指间区域的神经血管束形成花束状或树状排列。由于指间区域皮肤下方的空间厚且疏松，指间区域的树状结构长达2毫米。无论在哪个部位，每个小体的中央核心S100蛋白呈阳性，而小体内的核心和部分毛细血管对巢蛋白呈弱阳性。因为在成年人中尚未报道过肌腱鞘和甲床中的小体以及小体的花束状和树状排列，所以这些形态可能是胎儿特有的。《解剖学记录》，2017年。©2017威利期刊公司。《解剖学记录》，301:154 - 165，2018年。©2017威利期刊公司。
