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膝关节置换术后C反应蛋白水平与性别差异及置换类型的关系。

The relationship of C-reaktif protein level after knee artroplasty with gender difference and type of artroplasty.

作者信息

Altinayak Harun, Karatekin Yavuz Selim, Balta Orhan

机构信息

Department of Orthopaedics and Traumatology, Samsun Education and Research Hospital, Ilkadim, Turkey.

Department of Orthopaedics and Traumatology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.

出版信息

J Orthop Surg (Hong Kong). 2023 May-Aug;31(2):10225536231190309. doi: 10.1177/10225536231190309.

Abstract

PURPOSE

It was aimed to reveal the relationship between CRP level after knee arthroplasty and gender difference and arthroplasty type.

METHODS

Preoperative and postoperative (1st and 7th day, 1st and 3rd months) CRP values of the patients who underwent TKA or UKA were examined. The data were compared by categorizing them into primary male-female, secondary TKA-UKA groups.

RESULTS

967 patients were included in the study (151 male, 685 female in the TKA group and 25 male, 106 female in the UKA group) In the TKA group, the mean age was 67.38 in males and 65.54 in females. In the UKA group, the mean age was 58.72 in males and 57,63 in females. CRP values were found to be statistically significantly lower in females compared to males in the preoperative period, postoperative 1st and 3rd months in patients who underwent TKA ( < .05). In the UKA group, it was found to be significantly lower in females in the preoperative period and at the postoperative 3rd month, < .05). When the CRP values and their effect on the course of arthroplasty were evaluated according to the type of arthroplasty, there was no significant difference between the CRP values of the preoperative patients ( = .686). In addition, in the comparison made on the postoperative 1st day, 1st week, 1st month, and 3rd month, CRP values of the patient who underwent UKA were found to be significantly lower ( < .05). When analyzed separately by arthroplasty type, postoperative CRP values decreased to normal limits in 96.3% of patients who underwent TKA and 98.5% of patients who underwent UKA in the third month.

CONCLUSIONS

Our study showed that the uncomplicated course of CRP after TKA and UKA is gender-specific, and higher CRP values are observed in males than in females. The UKA group exhibited significantly lower postoperative CRP levels than the TKA group.

摘要

目的

旨在揭示膝关节置换术后CRP水平与性别差异及置换类型之间的关系。

方法

对接受全膝关节置换术(TKA)或单髁膝关节置换术(UKA)的患者术前及术后(第1天和第7天、第1个月和第3个月)的CRP值进行检查。通过将数据分为原发性男女组、继发性TKA-UKA组进行比较。

结果

本研究共纳入967例患者(TKA组男性151例,女性685例;UKA组男性25例,女性106例)。TKA组中,男性平均年龄为67.38岁,女性为65.54岁。UKA组中,男性平均年龄为58.72岁,女性为57.63岁。在接受TKA的患者中,术前、术后第1个月和第3个月,女性的CRP值在统计学上显著低于男性(P<0.05)。在UKA组中,术前及术后第3个月女性的CRP值显著更低(P<0.05)。根据置换类型评估CRP值及其对置换过程的影响时,术前患者的CRP值之间无显著差异(P=0.686)。此外,在术后第1天、第1周、第1个月和第3个月的比较中,接受UKA的患者的CRP值显著更低(P<0.05)。按置换类型分别分析时,TKA患者中有96.3%、UKA患者中有98.5%在术后第3个月CRP值降至正常范围。

结论

我们的研究表明,TKA和UKA术后CRP的正常过程具有性别特异性,男性的CRP值高于女性。UKA组术后CRP水平显著低于TKA组。

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