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经术前栓塞成功治疗的透明细胞室管膜瘤病例

Case of Clear Cell Ependymoma Successfully Treated with Preoperative Embolization.

作者信息

Haryu Shinya, Niizuma Kuniyasu, Endo Hidenori, Sato Kenichi, Watanabe Mika, Tominaga Teiji

机构信息

Department of Neurosurgery, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi, Japan.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

出版信息

J Neuroendovasc Ther. 2020;14(9):394-399. doi: 10.5797/jnet.cr.2020-0050. Epub 2020 Jun 9.

Abstract

OBJECTIVE

Clear cell ependymoma (CCE) is known to be very similar to hemangioblastoma (HB) in regards to neuroimaging and histopathology. We report a rare case of CCE in which successfully underwent preoperative embolization with a prior diagnosis of HB.

CASE PRESENTATION

A 58-year-old woman presented with vertigo for several months. MRI showed the right cerebellar tumor mimicking solid HB. DSA revealed the hypervascular tumor supplied by branches of the posterior inferior cerebellar artery (PICA). To reduce intraoperative bleeding, preoperative embolization was performed using n-butyl-2-cyanoacrylate (NBCA). A flow-guided microcatheter was guided to the proper feeders, and diluted NBCA was injected. Sufficient devascularization was achieved. The tumor was totally resected with minimal blood loss the next day. Postoperative pathological diagnosis was CCE.

CONCLUSION

This is the first report that preoperative embolization was performed to CCE with careful techniques and recent advanced devices. Since CCE has a poorer prognosis, preoperative embolization for safety total resection may be more important.

摘要

目的

透明细胞室管膜瘤(CCE)在神经影像学和组织病理学方面与血管母细胞瘤(HB)非常相似。我们报告一例罕见的CCE病例,该病例在术前诊断为HB的情况下成功接受了栓塞治疗。

病例介绍

一名58岁女性因眩晕数月就诊。磁共振成像(MRI)显示右侧小脑肿瘤,类似实性HB。数字减影血管造影(DSA)显示由小脑下后动脉(PICA)分支供血的高血管性肿瘤。为减少术中出血,使用正丁基-2-氰基丙烯酸酯(NBCA)进行术前栓塞。将血流导向微导管引导至合适的供血动脉,并注入稀释的NBCA。实现了充分的血管闭塞。次日,肿瘤在失血极少的情况下被完全切除。术后病理诊断为CCE。

结论

这是首例使用精细技术和最新先进设备对CCE进行术前栓塞的报告。由于CCE的预后较差,为安全全切进行术前栓塞可能更为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3882/10370905/73e470c55ce6/jnet-14-394-g001.jpg

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