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使用端端吻合器行直肠前切除术后的复发与生存情况

Recurrence and survival after anterior resection of the rectum using the end to end anastomotic stapler.

作者信息

Malmberg M, Graffner H, Ling L, Olsson S A

出版信息

Surg Gynecol Obstet. 1986 Sep;163(3):231-4.

PMID:3750178
Abstract

With the introduction of the end to end anastomotic stapler there has been an increase in the number of sphincter saving resections for carcinoma of the middle and distal part of the rectum. The results of earlier reports have indicated an increasing number of local recurrences possibly due to less extensive dissection of the lower pelvic area. Ninety-six patients, 46 males and 50 females, with a median age of 68 years (a range in age of 33 to 86 years) were operated upon between 1978 and 1981 for carcinoma of the rectum with anterior resection and stapled anastomosis have been analyzed. All patients were observed for more than three years (a median of 65 months and a range of 36 to 82 months). The hospital mortality rate was 5 per cent. The median distal margin was 2.5 centimeters (a range of 1 to 10 centimeters). Local recurrences occurred in 17 patients. No correlation between the grade of malignant disease and classification according to Dukes' staging and local recurrence was found. The median time between operation and the diagnosis of a local recurrence was 14 months (two to 62 months). Distant metastases developed in 14 of 83 patients who underwent operation for cure. The over-all five year survival rate was 64 per cent. The survival rate for 83 patients who underwent operation for cure was 71 per cent (96 per cent of Dukes' A, 72 per cent for Dukes' B, 45 per cent for Dukes' C and zero per cent for Dukes' D). It is concluded that the use of stapling devices has not been followed by a higher rate of local recurrence or a decreased five year survival rate and that this new technique can be used whenever technically possible.

摘要

随着端端吻合器的引入,直肠中下段癌保留括约肌切除术的数量有所增加。早期报告的结果表明,局部复发的数量不断增加,这可能是由于盆腔下部区域的解剖不够广泛。对1978年至1981年间接受直肠前切除术和吻合器吻合术治疗直肠癌的96例患者(46例男性和50例女性)进行了分析,中位年龄为68岁(年龄范围为33至86岁)。所有患者均接受了超过三年的观察(中位时间为65个月,范围为36至82个月)。医院死亡率为5%。远端切缘的中位距离为2.5厘米(范围为1至10厘米)。17例患者出现局部复发。未发现恶性疾病分级、Dukes分期与局部复发之间存在相关性。手术与局部复发诊断之间的中位时间为14个月(2至62个月)。83例接受根治性手术的患者中有14例发生远处转移。总体五年生存率为64%。83例接受根治性手术的患者的生存率为71%(Dukes A期为96%,Dukes B期为72%,Dukes C期为45%,Dukes D期为0%)。得出的结论是,使用吻合器并未导致更高的局部复发率或降低五年生存率,并且只要技术可行,就可以使用这种新技术。

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