Imai Naoya, Ishiguro Mitsunori, Yonezawa Shingo, Nonaka Yuko, Hara Shigeru, Fukazawa Seiji
Department of Neurosurgery, Shizuoka City Shizuoka Hospital, Shizuoka, Shizuoka, Japan.
J Neuroendovasc Ther. 2021;15(12):800-804. doi: 10.5797/jnet.oa.2020-0168. Epub 2021 Apr 22.
Endovascular therapy (EVT) is a well-documented treatment for acute occlusion of major cerebral arteries. We carried out in-hospital triage using the emergency large vessel occlusion (ELVO) screen, a pre-hospital scale for acute stroke, to diagnose EVT cases and considered its efficacy.
We investigated stroke cases examined within 24 hours of onset in a 6-month period beginning on March 15, 2019. The results of ELVO screen were retrospectively considered with the presence of atrial fibrillation and treatment of EVT.
A total of 146 cases were included. Of the 65 positive ELVO screen cases, 33 (51%) had large vessel occlusion (LVO). Of the 81 negative ELVO screen cases, 11 (14%) had LVO (sensitivity, 75%; specificity, 69%; positive predictive value, 51%; negative predictive value, 86%; accuracy, 71%; P <0.001). Among LVO cases, 16 of the 33 (48%) positive ELVO screen cases and 2 of the 11 (18%) negative ELVO screen cases were treated by EVT. Complications of atrial fibrillation were significantly more common in positive ELVO screen cases (P = 0.001). EVT was carried out in nearly half of the positive ELVO screen cases of atrial fibrillation, being a significantly higher rate (10 of 24 cases, 42%; P = 0.02).
The accuracy of EVT use increased in positive ELVO screen cases, particularly in those with atrial fibrillation. In-hospital triage using ELVO screen, a pre-hospital scale, significantly aided in selecting patients requiring EVT.
血管内治疗(EVT)是治疗大脑主要动脉急性闭塞的一种有充分文献记载的方法。我们使用急诊大血管闭塞(ELVO)筛查进行院内分诊,这是一种用于急性卒中的院前量表,以诊断EVT病例并评估其疗效。
我们调查了2019年3月15日开始的6个月内发病24小时内接受检查的卒中病例。回顾性分析ELVO筛查结果与房颤的存在及EVT治疗情况。
共纳入146例病例。在65例ELVO筛查阳性的病例中,33例(51%)存在大血管闭塞(LVO)。在81例ELVO筛查阴性的病例中,11例(14%)存在LVO(敏感性为75%;特异性为69%;阳性预测值为51%;阴性预测值为86%;准确性为71%;P<0.001)。在LVO病例中,33例ELVO筛查阳性病例中的16例(48%)和11例ELVO筛查阴性病例中的2例(18%)接受了EVT治疗。房颤并发症在ELVO筛查阳性病例中明显更常见(P = 0.001)。近一半的ELVO筛查阳性房颤病例接受了EVT治疗,比例显著更高(24例中的10例,42%;P = 0.02)。
在ELVO筛查阳性病例中,尤其是伴有房颤的病例,EVT使用的准确性有所提高。使用院前量表ELVO筛查进行院内分诊显著有助于选择需要EVT的患者。