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急性卒中合并紧急大血管闭塞筛查的诊断与管理

The Diagnosis and Management of Acute Stroke with Emergent Large Vessel Occlusion Screen.

作者信息

Imai Naoya, Ishiguro Mitsunori, Yonezawa Shingo, Nonaka Yuko, Hara Shigeru, Fukazawa Seiji

机构信息

Department of Neurosurgery, Shizuoka City Shizuoka Hospital, Shizuoka, Shizuoka, Japan.

出版信息

J Neuroendovasc Ther. 2021;15(12):800-804. doi: 10.5797/jnet.oa.2020-0168. Epub 2021 Apr 22.

Abstract

OBJECTIVE

Endovascular therapy (EVT) is a well-documented treatment for acute occlusion of major cerebral arteries. We carried out in-hospital triage using the emergency large vessel occlusion (ELVO) screen, a pre-hospital scale for acute stroke, to diagnose EVT cases and considered its efficacy.

METHODS

We investigated stroke cases examined within 24 hours of onset in a 6-month period beginning on March 15, 2019. The results of ELVO screen were retrospectively considered with the presence of atrial fibrillation and treatment of EVT.

RESULTS

A total of 146 cases were included. Of the 65 positive ELVO screen cases, 33 (51%) had large vessel occlusion (LVO). Of the 81 negative ELVO screen cases, 11 (14%) had LVO (sensitivity, 75%; specificity, 69%; positive predictive value, 51%; negative predictive value, 86%; accuracy, 71%; P <0.001). Among LVO cases, 16 of the 33 (48%) positive ELVO screen cases and 2 of the 11 (18%) negative ELVO screen cases were treated by EVT. Complications of atrial fibrillation were significantly more common in positive ELVO screen cases (P = 0.001). EVT was carried out in nearly half of the positive ELVO screen cases of atrial fibrillation, being a significantly higher rate (10 of 24 cases, 42%; P = 0.02).

CONCLUSION

The accuracy of EVT use increased in positive ELVO screen cases, particularly in those with atrial fibrillation. In-hospital triage using ELVO screen, a pre-hospital scale, significantly aided in selecting patients requiring EVT.

摘要

目的

血管内治疗(EVT)是治疗大脑主要动脉急性闭塞的一种有充分文献记载的方法。我们使用急诊大血管闭塞(ELVO)筛查进行院内分诊,这是一种用于急性卒中的院前量表,以诊断EVT病例并评估其疗效。

方法

我们调查了2019年3月15日开始的6个月内发病24小时内接受检查的卒中病例。回顾性分析ELVO筛查结果与房颤的存在及EVT治疗情况。

结果

共纳入146例病例。在65例ELVO筛查阳性的病例中,33例(51%)存在大血管闭塞(LVO)。在81例ELVO筛查阴性的病例中,11例(14%)存在LVO(敏感性为75%;特异性为69%;阳性预测值为51%;阴性预测值为86%;准确性为71%;P<0.001)。在LVO病例中,33例ELVO筛查阳性病例中的16例(48%)和11例ELVO筛查阴性病例中的2例(18%)接受了EVT治疗。房颤并发症在ELVO筛查阳性病例中明显更常见(P = 0.001)。近一半的ELVO筛查阳性房颤病例接受了EVT治疗,比例显著更高(24例中的10例,42%;P = 0.02)。

结论

在ELVO筛查阳性病例中,尤其是伴有房颤的病例,EVT使用的准确性有所提高。使用院前量表ELVO筛查进行院内分诊显著有助于选择需要EVT的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14c3/10370933/aa2d377e8d87/jnet-15-800-g001.jpg

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