Tsumoto Tomoyuki, Yabuzaki Hajime, Nishiyama Akira, Tanaka Yuko, Matsuda Yoshikazu, Terada Tomoaki
Department of Neurological Surgery, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.
J Neuroendovasc Ther. 2020;14(12):565-571. doi: 10.5797/jnet.ra.2020-0059. Epub 2020 Jun 25.
Cavernous sinus (CS) dural arteriovenous fistulas (AVF), which are most common in middle-aged females, present with benign symptoms such as exophthalmos, chemosis, and orbital bruit. Benign CS dural AVF without cortical venous drainage (CVD) have the rare potential for development of CVD with neurological symptoms, even without treatment. On the other hand, aggressive type AVF with CVD can cause more aggressive symptoms such as cerebral hemorrhage. As symptoms are highly related to the drainage pattern, it is important to understand the anatomy of the CS itself, shunt point, and draining vein when treating the lesion. In general, the drainage route is gradually diminished by thrombosis and compartmentalization within the CS according to progression of the angiographical stage. At the restrictive stage, the disease is usually treated by endovascular treatment, particularly transvenous embolization.
海绵窦(CS)硬脑膜动静脉瘘(AVF)在中年女性中最为常见,表现为眼球突出、结膜水肿和眼眶杂音等良性症状。无皮质静脉引流(CVD)的良性CS硬脑膜AVF即使未经治疗也有罕见的发展为伴有神经症状的CVD的可能性。另一方面,伴有CVD的侵袭性AVF可导致更具侵袭性的症状,如脑出血。由于症状与引流模式高度相关,在治疗病变时了解CS本身的解剖结构、分流点和引流静脉很重要。一般来说,根据血管造影分期的进展,引流途径会因CS内的血栓形成和分隔而逐渐减少。在限制期,该病通常通过血管内治疗,尤其是经静脉栓塞来治疗。