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伴有布加综合征病史的横纹肌样脑膜瘤:一例病例报告及文献复习

Rhabdoid meningioma with a history of Budd-Chiari syndrome: a case report and review of the literature.

作者信息

Zeng Ying, Zhang Jing, Jian Wei, Zhang Yong, Yang Ying, Li Rongqing, Fu Qiaofen

机构信息

Department of Radiation Oncology, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Department of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, China.

出版信息

Front Oncol. 2023 Jul 11;13:1209244. doi: 10.3389/fonc.2023.1209244. eCollection 2023.

Abstract

BACKGROUND

Rhabdoid meningioma and Budd-Chiari syndrome are both extremely rare, and there is no report describing the two diseases occurring in the same patient thus far. Herein, we showed an unusual case of rhabdoid meningioma with a history of Budd-Chiari syndrome.

CASE PRESENTATION

The man was found to have abnormal liver function during physical examination in 2016 at 36 and was not paid attention to it. In 2019, he went to Beijing YouAn Hospital Affiliated to Capital Medical University for the decompensation of cirrhosis and was diagnosed with Budd-Chiari syndrome, subsequent angiography of the inferior vena cava combined with balloon dilatation were performed, the anticoagulation and hepatoprotective therapy were performed for a long time. When he turned 40 who had magnetic resonance imaging (MRI) that showed a left frontotemporal lobe space-occupying lesion, and postoperative pathological examination confirmed rhabdoid meningioma. He underwent surgery and postoperative adjuvant radiotherapy, but then he developed severe psychiatric symptoms and eventually succumbed to a lung infection two months after treatment.

CONCLUSIONS

Budd-Chiari syndrome and Rhabdoid meningiomas are both extremely rare diseases. To the best of our knowledge, there is no report that the two rare diseases occurred in the same patient, and this is the first case. However, whether there is any link between the two diseases is unclear, more researches are needed to confirm it in the future.

摘要

背景

横纹肌样脑膜瘤和布加综合征都极为罕见,迄今为止尚无关于这两种疾病发生在同一患者身上的报道。在此,我们展示了一例具有布加综合征病史的罕见横纹肌样脑膜瘤病例。

病例介绍

该男子于2016年36岁时体检发现肝功能异常,但未予以重视。2019年,他前往首都医科大学附属北京佑安医院就诊,因肝硬化失代偿被诊断为布加综合征,随后进行了下腔静脉血管造影联合球囊扩张术,并长期进行抗凝和保肝治疗。40岁时,他进行了磁共振成像(MRI)检查,显示左额颞叶占位性病变,术后病理检查确诊为横纹肌样脑膜瘤。他接受了手术及术后辅助放疗,但随后出现严重精神症状,最终在治疗两个月后死于肺部感染。

结论

布加综合征和横纹肌样脑膜瘤均为极为罕见的疾病。据我们所知,尚无这两种罕见疾病发生在同一患者身上的报道,而本病例为首例。然而,这两种疾病之间是否存在任何关联尚不清楚,未来需要更多研究予以证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5c5/10370419/840c29aabf55/fonc-13-1209244-g001.jpg

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