Eling U Kh
Tsitol Genet. 1986 May-Jun;20(3):180-90.
The data are presented in favour of nonthresholdness of the dose-effect relationships in exposure of mouse germ cells to chemical mutagens. The data were obtained by the method of dominant lethal mutations and by the analysis of specific locus mutations with single and fractionated treatment at different germ cell stages.
这些数据表明,小鼠生殖细胞暴露于化学诱变剂时,剂量效应关系不存在阈值。这些数据是通过显性致死突变方法以及在不同生殖细胞阶段进行单次和分次处理的特定基因座突变分析获得的。