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2 型糖尿病患者伴痛性糖尿病周围神经病变的临床评估:来自阿拉伯联合酋长国侨民的经验教训。

Clinical evaluation of painful diabetes peripheral neuropathy in type 2 diabetes patients: Lessons from expatriates in the United Arab Emirates.

机构信息

College of Health Sciences, Gulf Medical University, Ajman, United Arab Emirates.

College of Healthcare Management and Economics, Gulf Medical University, Ajman, United Arab Emirates.

出版信息

Diabetes Metab Syndr. 2023 Sep;17(9):102832. doi: 10.1016/j.dsx.2023.102832. Epub 2023 Jul 23.

Abstract

BACKGROUND

The high prevalence of Type 2 Diabetes (T2D) in the United Arab Emirates makes it imperative to screen and manage diabetes peripheral neuropathy (DPN) as a priority. Considering the high number of expats from different ethnicity a more thorough approach is necessary. Unfortunately, there are very few studies addressing this issue.

METHODS

The study uses the chi-square test to investigate the dependence of the progression of DNP on ethnic origin. The study uses Pearson Correlation to find the association between three prevalent scales used for the measurement of painful diabetes peripheral neuropathy. Student t-test was used further to investigate the significance of the association.

RESULTS

With a p-value (0.004) and p-value (0.015), the study concludes that DPN risk is dependent on the ethnic origin of the residents. The study further found that there is a significant association between three scales for measuring painful diabetes peripheral neuropathy (pDNP), Douleur Neuropathique en 4 questions (DN4), Neurological Symptoms Score (NSS), and Leeds Assessment of Neuropathic Symptoms and Signs (LANNS). The p-value for all pairwise comparisons for the strength of association between scales was found significant at the level of significance 0.05.

CONCLUSION

The study concludes that the risk of DNP is high in Arab-origin residents in UAE and the reasons behind the finding need to be empirically tested to customize its management. The study further finds a significant association between the score of the three scales used for measuring pDNP.

摘要

背景

在阿拉伯联合酋长国,2 型糖尿病(T2D)的高发率使得筛查和管理糖尿病周围神经病变(DPN)成为当务之急。考虑到来自不同种族的大量外籍人士,需要采取更全面的方法。不幸的是,很少有研究涉及这个问题。

方法

该研究使用卡方检验来研究 DPN 进展是否取决于种族起源。研究使用皮尔逊相关系数来发现用于测量疼痛性糖尿病周围神经病变的三种常用量表之间的关联。进一步使用学生 t 检验来研究关联的显著性。

结果

p 值(0.004)和 p 值(0.015)表明,DPN 风险取决于居民的种族起源。研究还发现,用于测量疼痛性糖尿病周围神经病变的三种量表(pDNP)、4 个问题的神经病变疼痛量表(DN4)、神经症状评分(NSS)和利兹神经病症状和体征评估量表(LANNS)之间存在显著关联。所有量表之间关联强度的两两比较的 p 值在显著性水平 0.05 时均具有统计学意义。

结论

该研究得出结论,阿联酋阿拉伯裔居民患 DPN 的风险较高,需要通过实证检验来确定其管理方法。研究还发现,用于测量 pDNP 的三种量表的评分之间存在显著关联。

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