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藤壶光感受器中敏感度变化与反应时间尺度之间的关系。

The relation between sensitivity changes and response time scale in the barnacle photoreceptor.

作者信息

Hanani M

出版信息

Vision Res. 1986;26(6):819-25. doi: 10.1016/0042-6989(86)90140-9.

DOI:10.1016/0042-6989(86)90140-9
PMID:3750865
Abstract

Responses to brief light flashes were recorded intracellularly from the photoreceptors of the barnacle in order to study the relation between changes in sensitivity and latency. Conditioning lights either increased the response to a test flash (facilitation) or reduced it (desensitization). In both cases there was a shortening of the response latency. Similar observations were made when background illumination was used instead of conditioning lights. These effects were not qualitatively altered when the extracellular Ca2+ concentration was lowered. The results suggest that facilitation is not the result of a reduction of intracellular Ca2+ concentration; i.e. it is not the reverse of desensitization. Since during facilitation there is an increase in photoresponse associated with latency shortening it can be suggested that the underlying mechanism is an enhancement of the effective light intensity. The experiments do not provide quantitative evidence for this idea.

摘要

为了研究敏感性变化与潜伏期之间的关系,从藤壶的光感受器细胞内记录了对短暂闪光的反应。条件光要么增加对测试闪光的反应(易化),要么降低反应(脱敏)。在这两种情况下,反应潜伏期都缩短了。当使用背景光照代替条件光时,也得到了类似的观察结果。当细胞外Ca2+浓度降低时,这些效应在性质上没有改变。结果表明,易化不是细胞内Ca2+浓度降低的结果;也就是说,它不是脱敏的相反过程。由于在易化过程中,光反应增加且潜伏期缩短,因此可以认为潜在机制是有效光强度的增强。这些实验没有为这一观点提供定量证据。

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