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光学相干断层扫描:聚焦巩膜炎患者黄斑病变

Optical Coherence Tomography: Focus on the Pathology of Macula in Scleritis Patients.

作者信息

Smeller Lilla, Toth-Molnar Edit, Sohar Nicolette

机构信息

Department of Ophthalmology, University of Szeged, 6720 Szeged, Hungary.

出版信息

J Clin Med. 2023 Jul 21;12(14):4825. doi: 10.3390/jcm12144825.

Abstract

UNLABELLED

Optical coherence tomography (OCT) is a non-invasive imaging technique for high-resolution, cross-sectional tissue imaging of the eye. During the past two and a half decades, OCT has become an essential tool in ophthalmology. It is a painless method for examining details of ocular structures in vivo with high resolution that has revolutionized patient care following and treating scleritis patients.

METHODS

Twenty-four patients diagnosed with scleritis were selected for this study. All of the patients went through basic ophthalmological examinations, such as visual acuity testing (VA), intraocular pressure measurement (IOP), slit lamp examination, ophthalmoscopic examination, and OCT. OCT examinations were taken by SD-OCT Spectralis OCT system (Heidelberg Engineering, Heidelberg, Germany).

RESULTS

Twenty-seven eyes of 24 patients (7 males and 17 females) were included in this study, who were diagnosed with scleritis. OCT examinations showed epiretinal membrane (ERM) in three patients (12%), cystoid macular edema (CME) (three cases, 12%), diffuse macular edema (DME) (one case, 4%), and serous retinal detachment (SRD) (one case, 4%).

CONCLUSIONS

OCT proved to be a valuable, non-invasive method for detecting macular pathology in patients with scleritis. Despite the best treatment regimen applied, macular involvement resulting in reduced visual acuity (VA) can develop, which we could detect with OCT since macular edema (ME) is the leading cause of decreased vision due to the damaged outer blood-retina barrier (BRB) in inflammation. OCT investigation is a highly important method for early detection of ocular complications in scleritis in order to prevent blindness.

摘要

未标注

光学相干断层扫描(OCT)是一种用于眼部高分辨率横断面组织成像的非侵入性成像技术。在过去二十五年中,OCT已成为眼科的一项重要工具。它是一种无痛方法,可在体内高分辨率检查眼部结构细节,彻底改变了巩膜炎患者的后续护理和治疗方式。

方法

本研究选取了24例诊断为巩膜炎的患者。所有患者均接受了基本眼科检查,如视力测试(VA)、眼压测量(IOP)、裂隙灯检查、检眼镜检查和OCT。OCT检查采用SD-OCT Spectralis OCT系统(德国海德堡海德堡工程公司)进行。

结果

本研究纳入了24例患者(7例男性和17例女性)的27只眼,这些患者均被诊断为巩膜炎。OCT检查显示3例患者(12%)有视网膜前膜(ERM),3例(12%)有黄斑囊样水肿(CME),1例(4%)有弥漫性黄斑水肿(DME),1例(4%)有浆液性视网膜脱离(SRD)。

结论

OCT被证明是检测巩膜炎患者黄斑病变的一种有价值的非侵入性方法。尽管采用了最佳治疗方案,但仍可能发生导致视力下降(VA)的黄斑受累情况,由于炎症中受损的外层血视网膜屏障(BRB)导致黄斑水肿(ME)是视力下降的主要原因,我们可以通过OCT检测到这种情况。OCT检查是早期发现巩膜炎眼部并发症以预防失明的一项非常重要的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a04f/10381547/0c1c29e113eb/jcm-12-04825-g001.jpg

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