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比较墨西哥西部城市地区先兆子痫与血压正常的产后妇女的中心动脉压。

Comparison of Central Aortic Pressure between Women with Preeclampsia and Normotensive Postpartum Women from an Urban Region of Western Mexico.

机构信息

Department of Human Reproduction, Growth and Child Development, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, 44340 Guadalajara, Jalisco, Mexico.

Department of Obstetrics, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, 44200 Guadalajara, Jalisco, Mexico.

出版信息

Medicina (Kaunas). 2023 Jul 21;59(7):1343. doi: 10.3390/medicina59071343.

Abstract

: Central aortic pressure (CAP) can be measured through noninvasive methods, and CAP wave analysis can provide information about arterial stiffness. The objective of this study was to compare CAP in women with preeclampsia and normotensive postpartum women from an urban region in western Mexico. We recruited 78 women in immediate puerperium, including 39 with preeclampsia and 39 with normotension, who received delivery care in our hospital between September 2017 and January 2018. Pulse wave analysis was used to assess central hemodynamics as well as arterial stiffness with an oscillometric device. For this purpose, the measurement of the wave of the left radial artery was obtained with a wrist applanation tonometer and the ascending aortic pressure wave was generated using the accompanying software (V 1.1, Omron, Japan). Additionally, the systolic CAP, diastolic pressure, pulse pressure, heart rate, and rise rate adjusted for a heart rate of 75 bpm were determined. The radial pulse wave was calibrated using the diastolic and mean arterial pressures obtained from the left brachial artery. For all the statistical analyses, we considered < 0.05 to be significant. The results were as follows: a systolic CAP of 125.40 (SD 15.46) vs. 112.10 (SD 10.12) with < 0.0001 for women with and without preeclampsia, respectively. Systolic CAP was significantly elevated in women with preeclampsia and could indicate an elevated risk of cardiovascular disease. CAP is an important parameter that can be measured in this group of patients and is significantly elevated in women with postpartum preeclampsia, even when the brachial blood pressure is normal.

摘要

: 中心动脉压(CAP)可通过无创方法进行测量,而 CAP 波分析可提供动脉僵硬度的信息。本研究的目的是比较墨西哥西部一个城市地区患有先兆子痫的女性和血压正常的产后女性的 CAP。我们招募了 78 名产后立即的女性,包括 39 名患有先兆子痫的女性和 39 名血压正常的女性,她们在我们医院接受了 2017 年 9 月至 2018 年 1 月期间的分娩护理。使用脉搏波分析评估中心血液动力学以及使用示波法设备评估动脉僵硬度。为此,使用手腕平板血压计获得左侧桡动脉波的测量值,并使用随附的软件(V 1.1,欧姆龙,日本)生成升主动脉压力波。此外,还确定了校正为 75 bpm 的心率的收缩期 CAP、舒张压、脉压、心率和上升率。使用从左侧肱动脉获得的舒张压和平均动脉压校准桡动脉脉搏波。对于所有统计分析,我们认为 < 0.05 为显著。结果如下:收缩期 CAP 分别为 125.40(SD 15.46)和 112.10(SD 10.12),患有和不患有先兆子痫的女性之间差异具有统计学意义(< 0.0001)。患有先兆子痫的女性的收缩期 CAP 显著升高,这可能表明心血管疾病的风险增加。CAP 是可以在这群患者中测量的重要参数,并且在产后患有先兆子痫的女性中显著升高,即使肱动脉血压正常也是如此。

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[Central Aortic Pressure: Reference and Diagnostic Values].
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Indications for delivery in pre-eclampsia.子痫前期的分娩指征。
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