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当前实体器官移植受者疱疹病毒感染管理的观点。

Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients.

机构信息

Department of Internal Medicine, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.

Erasmus MC Transplant Institute, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.

出版信息

Viruses. 2023 Jul 21;15(7):1595. doi: 10.3390/v15071595.

Abstract

Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive therapy. We aim to increase awareness and understanding of HHV disease burden in SOTRs by providing an overview of current prevention and management strategies as described in the literature and guidelines. We discuss challenges in both prevention and treatment as well as future perspectives.

摘要

实体器官移植受者(SOTR)由于使用免疫抑制疗法,存在发生人类疱疹病毒(HHV)相关发病率和死亡率的高风险。我们旨在通过概述文献和指南中描述的当前预防和管理策略,提高对 SOTR 中 HHV 疾病负担的认识和理解。我们讨论了预防和治疗方面的挑战以及未来的展望。

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