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尿道 Bulkamid® 注射治疗失败的尿道中段吊带术后:分步视频。

Urethral Bulkamid® injection after failed midurethral sling: a step-by-step video.

机构信息

Department of Gynecology, Division of Gynecology and Obstetrics, University Medical Center Ljubljana, Ljubljana, Slovenia.

Department of Gynecology and Obstetrics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Int Urogynecol J. 2023 Nov;34(11):2843-2845. doi: 10.1007/s00192-023-05608-z. Epub 2023 Jul 29.

DOI:10.1007/s00192-023-05608-z
PMID:37515641
Abstract

INTRODUCTION AND HYPOTHESIS

Bulking agents are a minimally invasive treatment option for women with stress urinary incontinence (SUI) or stress-predominant mixed urinary incontinence (MUI). Recurrent SUI is a major challenge for most clinicians because there is little evidence in the literature on the best option after midurethral sling (MUS) failure.

METHODS

Bulkamid® (Contura International A/S), a urethral bulking agent, is a homogenous gel without particles, consisting of a polyacrylamide hydrogel that is nonbiodegradable.

RESULTS

In this video case report, we demonstrate the Bulkamid® injection procedure. This procedure can be carried out as an office-based procedure under local anesthesia, with no down time and only minor possible complications.

CONCLUSIONS

We consider it a valid option for patients with recurrent or persistent SUI after failed MUS surgery.

摘要

简介和假设

对于压力性尿失禁(SUI)或以压力为主的混合性尿失禁(MUI)女性,膨体剂是一种微创治疗选择。大多数临床医生认为复发性 SUI 是一个主要挑战,因为在中尿道吊带(MUS)失败后,文献中几乎没有关于最佳选择的证据。

方法

Bulkamid®(Contura International A/S)是一种尿道膨体剂,是一种无颗粒的均匀凝胶,由不可生物降解的聚丙烯酰胺水凝胶组成。

结果

在这个视频病例报告中,我们展示了 Bulkamid®注射程序。该程序可以在局麻下作为门诊手术进行,无需停机时间,只有轻微的可能并发症。

结论

我们认为对于 MUS 手术后复发或持续性 SUI 的患者,这是一种有效的选择。

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本文引用的文献

1
Tension-Free Vaginal Tape and Polyacrylamide Hydrogel Injection for Primary Stress Urinary Incontinence: 3-Year Followup from a Randomized Clinical Trial.经阴道无张力吊带术与聚丙烯酰胺水凝胶注射治疗原发性压力性尿失禁:一项随机临床试验的 3 年随访结果。
J Urol. 2022 Sep;208(3):658-667. doi: 10.1097/JU.0000000000002720. Epub 2022 Aug 5.
2
Update on Urethral Bulking for Stress Urinary Incontinence in Women.女性压力性尿失禁尿道填充治疗进展。
Curr Urol Rep. 2022 Oct;23(10):203-209. doi: 10.1007/s11934-022-01099-5. Epub 2022 Jul 4.
3
Urethral bulking agents for the treatment of recurrent stress urinary incontinence: A systematic review and meta-analysis.
尿道填充剂治疗复发性压力性尿失禁:系统评价和荟萃分析。
Maturitas. 2022 Sep;163:28-37. doi: 10.1016/j.maturitas.2022.05.007. Epub 2022 May 26.
4
European Association of Urology Guidelines on the Diagnosis and Management of Female Non-neurogenic Lower Urinary Tract Symptoms. Part 1: Diagnostics, Overactive Bladder, Stress Urinary Incontinence, and Mixed Urinary Incontinence.欧洲泌尿外科学会女性非神经源性下尿路症状诊断与管理指南。第 1 部分:诊断、膀胱过度活动症、压力性尿失禁和混合性尿失禁。
Eur Urol. 2022 Jul;82(1):49-59. doi: 10.1016/j.eururo.2022.01.045. Epub 2022 Feb 23.
5
Urethral bulking agents for the treatment of stress urinary incontinence in women: A systematic review.尿道填充剂治疗女性压力性尿失禁:系统评价。
Neurourol Urodyn. 2021 Aug;40(6):1349-1388. doi: 10.1002/nau.24696. Epub 2021 May 20.
6
Seven-year efficacy and safety outcomes of Bulkamid for the treatment of stress urinary incontinence.布利卡米德治疗压力性尿失禁的 7 年疗效和安全性结果。
Neurourol Urodyn. 2021 Jan;40(1):502-508. doi: 10.1002/nau.24589. Epub 2021 Jan 7.
7
Tension-Free Vaginal Tape Surgery versus Polyacrylamide Hydrogel Injection for Primary Stress Urinary Incontinence: A Randomized Clinical Trial.经阴道无张力吊带术与聚丙烯酰胺水凝胶注射治疗原发性压力性尿失禁的随机临床试验。
J Urol. 2020 Feb;203(2):372-378. doi: 10.1097/JU.0000000000000517. Epub 2019 Sep 3.