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鞘内注射巴氯芬治疗改善严重脑瘫患儿的功能和生活质量。

Intracerebroventricular baclofen therapy improves function and quality of life in a child with severe cerebral palsy.

机构信息

Department of Neurosurgery, Clinica de Dor E Funcional (CDF), Sao Paulo, SP, Brazil.

Division of Neurosurgery, Clinics Hospital, University of Sao Paulo, Sao Paulo, SP, Brazil.

出版信息

Childs Nerv Syst. 2023 Dec;39(12):3639-3642. doi: 10.1007/s00381-023-06084-y. Epub 2023 Jul 29.

DOI:10.1007/s00381-023-06084-y
PMID:37515719
Abstract

Limited therapies are available for severe cerebral palsy children (CP) with complex movement disorders, especially when both dystonia and spasticity are present. In this publication, we present the improvement of a child with severe CP after intracerebroventricular baclofen therapy. The treatment can impact not just the movement disorders but also on the quality of life of the child and caregivers. Global functional improvements can be observed on the 6-month follow-up.

摘要

对于伴有复杂运动障碍的严重脑瘫(CP)儿童,治疗方法有限,尤其是当同时存在肌张力障碍和痉挛时。在本出版物中,我们介绍了一例接受脑室内巴氯芬治疗后严重 CP 儿童的改善情况。该治疗不仅可以影响运动障碍,还可以提高儿童及其照顾者的生活质量。在 6 个月的随访中可以观察到整体功能的改善。

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Intracerebroventricular baclofen therapy improves function and quality of life in a child with severe cerebral palsy.鞘内注射巴氯芬治疗改善严重脑瘫患儿的功能和生活质量。
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引用本文的文献

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本文引用的文献

1
Intraventricular baclofen for dystonia: techniques and outcomes. Clinical article.用于治疗肌张力障碍的脑室内巴氯芬:技术与疗效。临床文章。
J Neurosurg Pediatr. 2009 Jan;3(1):11-4. doi: 10.3171/2008.10.PEDS0847.
2
Combined ventral and dorsal rhizotomies for dystonic and spastic extremities. Report of six cases.用于治疗手足肌张力障碍和痉挛的联合腹侧与背侧神经根切断术。6例报告。
J Neurosurg. 2007 Oct;107(4 Suppl):324-7. doi: 10.3171/PED-07/10/324.
3
Predictors of poor outcome after selective dorsal rhizotomy in treatment of spastic cerebral palsy.
选择性脊神经后根切断术治疗痉挛性脑瘫后预后不良的预测因素。
Childs Nerv Syst. 2006 Jan;22(1):60-6. doi: 10.1007/s00381-005-1160-2. Epub 2005 May 19.
4
Spinal deformity following selective dorsal rhizotomy.
J Pediatr Orthop. 2004 Jan-Feb;24(1):30-6. doi: 10.1097/00004694-200401000-00007.