Edgren J, Laasonen L, Groop P H, Groop L
Acta Radiol Diagn (Stockh). 1986 May-Jun;27(3):265-7. doi: 10.1177/028418518602700302.
A double blind urographic study with the ionic contrast medium metrizoate or the non-ionic medium iohexol was performed on 69 insulin dependent diabetic patients. Metrizoate caused 24 per cent and iohexol 11 per cent mild adverse reactions and metrizoate a significant decrease in creatinine clearance values. Thus iohexol turned out to be better tolerated by these diabetic patients than metrizoate.
对69例胰岛素依赖型糖尿病患者进行了一项双盲尿路造影研究，使用离子型造影剂甲泛葡胺或非离子型造影剂碘海醇。甲泛葡胺引起24%的轻度不良反应，碘海醇引起11%的轻度不良反应，且甲泛葡胺使肌酐清除率值显著降低。因此，这些糖尿病患者对碘海醇的耐受性优于甲泛葡胺。
