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股-髂动脉阻塞的选择性链激酶溶栓治疗

Selective streptokinase fibrinolysis in femoro-iliac arterial obstruction.

作者信息

Sørensen K, Hegedüs V

出版信息

Acta Radiol Diagn (Stockh). 1986 May-Jun;27(3):279-83. doi: 10.1177/028418518602700305.

DOI:10.1177/028418518602700305
PMID:3751674
Abstract

Percutaneous transluminal angioplasty of iliac and femoral arteries was in 17 patients combined with selective intra-arterial streptokinase treatment. The patients were divided into two groups, one given low dose long-term therapy and the other high dose short-term therapy. The experiences obtained during an observation period of over one year revealed greater benefit from high dose short-term therapy. It seems that the major cause of complications must be attributed to the development of a high level of streptokinase antibodies during low dose long-term therapy.

摘要

17例髂动脉和股动脉经皮腔内血管成形术患者同时接受了选择性动脉内链激酶治疗。患者被分为两组,一组接受低剂量长期治疗,另一组接受高剂量短期治疗。在一年多的观察期内获得的经验表明,高剂量短期治疗的益处更大。低剂量长期治疗期间出现高水平链激酶抗体似乎是并发症的主要原因。

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