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基层医疗抗生素审核和反馈干预的最佳实践指南:联合抗菌药物耐药性规划倡议(JPIAMR)的初级保健抗生素审核和反馈网络(JPIAMR-PAAN)的改良 Delphi 研究

Best practice guidance for antibiotic audit and feedback interventions in primary care: a modified Delphi study from the Joint Programming Initiative on Antimicrobial resistance: Primary Care Antibiotic Audit and Feedback Network (JPIAMR-PAAN).

机构信息

Public Health Ontario, 480 University Ave, Ste 300, Toronto, ON, M5G 1V2, Canada.

Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.

出版信息

Antimicrob Resist Infect Control. 2023 Jul 29;12(1):72. doi: 10.1186/s13756-023-01279-z.

Abstract

BACKGROUND

Primary care is a critical partner for antimicrobial stewardship efforts given its high human antibiotic usage. Peer comparison audit and feedback (A&F) is often used to reduce inappropriate antibiotic prescribing. The design and implementation of A&F may impact its effectiveness. There are no best practice guidelines for peer comparison A&F in antibiotic prescribing in primary care.

OBJECTIVE

To develop best practice guidelines for peer comparison A&F for antibiotic prescribing in primary care in high income countries by leveraging international expertise via the Joint Programming Initiative on Antimicrobial Resistance-Primary Care Antibiotic Audit and Feedback Network.

METHODS

We used a modified Delphi process to achieve convergence of expert opinions on best practice statements for peer comparison A&F based on existing evidence and theory. Three rounds were performed, each with online surveys and virtual meetings to enable discussion and rating of each best practice statement. A five-point Likert scale was used to rate consensus with a median threshold score of 4 to indicate a consensus statement.

RESULTS

The final set of guidelines include 13 best practice statements in four categories: general considerations (n = 3), selecting feedback recipients (n = 1), data and indicator selection (n = 4), and feedback delivery (n = 5).

CONCLUSION

We report an expert-derived best practice recommendations for designing and evaluating peer comparison A&F for antibiotic prescribing in primary care. These 13 statements can be used by A&F designers to optimize the impact of their quality improvement interventions, and improve antibiotic prescribing in primary care.

摘要

背景

初级保健是抗菌药物管理工作的重要合作伙伴,因为它的抗生素使用率很高。同行比较审核和反馈(A&F)通常用于减少不适当的抗生素处方。A&F 的设计和实施可能会影响其效果。在初级保健中,针对抗生素处方的同行比较 A&F 没有最佳实践指南。

目的

通过利用抗菌药物耐药性联合规划倡议 - 初级保健抗生素审核和反馈网络的国际专业知识,制定高收入国家初级保健中针对抗生素处方的同行比较 A&F 的最佳实践指南。

方法

我们使用改良 Delphi 流程,根据现有证据和理论,就同行比较 A&F 的最佳实践陈述达成专家意见的趋同。进行了三轮,每轮都有在线调查和虚拟会议,以促进对每个最佳实践陈述的讨论和评分。使用五点李克特量表对共识进行评分,中位数阈值得分为 4 表示共识陈述。

结果

最终的指南包括四个类别的 13 条最佳实践陈述:一般注意事项(n=3)、选择反馈接收者(n=1)、数据和指标选择(n=4)和反馈传递(n=5)。

结论

我们报告了一套针对设计和评估初级保健中抗生素处方的同行比较 A&F 的专家推荐的最佳实践建议。这些 13 条陈述可用于 A&F 设计人员优化其质量改进干预措施的影响,并改善初级保健中的抗生素处方。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2a7/10387210/66ad005d872b/13756_2023_1279_Fig1_HTML.jpg

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