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临床运动试验是否允许在被转诊至心脏康复的患者中确定运动阈值?

Do Clinical Exercise Tests Permit Exercise Threshold Identification in Patients Referred to Cardiac Rehabilitation?

机构信息

School of Kinesiology, University of Western Ontario, London, Ontario, Canada; Lawson Health Research Institute, London, Ontario, Canada.

Lawson Health Research Institute, London, Ontario, Canada; Cardiac Rehabilitation and Secondary Prevention Program, St Joseph's Health Care, London, Ontario, Canada.

出版信息

Can J Cardiol. 2023 Nov;39(11):1701-1711. doi: 10.1016/j.cjca.2023.07.029. Epub 2023 Jul 28.

DOI:10.1016/j.cjca.2023.07.029
PMID:37517474
Abstract

BACKGROUND

To evaluate the feasibility of "threshold-based" aerobic exercise prescription in cardiovascular disease, we aimed to quantify the proportion of patients whose clinical cardiopulmonary exercise test (CPET) permit identification of estimated lactate threshold (θ) and respiratory compensation point (RCP) and to characterize the variability at which these thresholds occur.

METHODS

Breath-by-breath CPET data of 1102 patients (65 ± 12 years) referred to cardiac rehabilitation were analyzed to identify peak O uptake (V˙O; mL·min and mL·kg·min) and θ and RCP (reported as V˙O, %V˙O, and %peak heart rate [%HR]). Patients were grouped by the presence or absence of thresholds: group 0: neither θ nor RCP; group 1: θ only; and group 2: both θ and RCP.

RESULTS

Mean V˙O was 1523 ± 627 mL·min (range: 315-3789 mL·min) or 18.0 ± 6.5 mL·kg·min (5.2-46.5 mL·kg·min) and HR was 123 ± 24 beats per minute (bpm) (52 bpm-207 bpm). There were 556 patients (50%) in group 0, 196 (18%) in group 1, and 350 (32%) in group 2. In group 1, mean θ was 1240 ± 410 mL·min (580-2560 mL·min), 75% ± 8%V˙O (52%-92%V˙O), or 84% ± 6%HR (64%-96%HR). In group 2, θ was 1390 ± 360 mL·min (640-2430 mL·min), 70% ± 8%V˙O (41%-88%V˙O), or 78% ± 7%HR (52%-96%HR), and RCP was 1680 ± 440 mL·min (730-3090 mL·min), 84% ± 7%V˙O (54%-99%V˙O), or 87% ± 6%HR (59%-99%HR). Compared with group 1, θ in group 2 occurred at a higher V˙O but lower %V˙O and %HR (P < 0.05).

CONCLUSIONS

Only 32% of CPETs exhibited both θ and RCP despite flexibility in protocol options. Commonly used step-based protocols are suboptimal for "threshold-based" exercise prescription.

摘要

背景

为了评估心血管疾病中“基于阈值”的有氧运动处方的可行性,我们旨在量化有多少患者的临床心肺运动试验(CPET)可以确定估计的乳酸阈(θ)和呼吸补偿点(RCP),并描述这些阈值出现的可变性。

方法

对 1102 名(65 ± 12 岁)接受心脏康复治疗的患者的呼吸逐次 CPET 数据进行分析,以确定峰值 O 摄取量(V˙O;mL·min 和 mL·kg·min)和 θ 和 RCP(以 V˙O、%V˙O 和 %峰值心率 [%HR]报告)。根据是否存在阈值将患者分为三组:组 0:既没有 θ 也没有 RCP;组 1:只有 θ;组 2:既有 θ 又有 RCP。

结果

平均 V˙O 为 1523 ± 627 mL·min(范围:315-3789 mL·min)或 18.0 ± 6.5 mL·kg·min(5.2-46.5 mL·kg·min),心率为 123 ± 24 次/分钟(bpm)(52 bpm-207 bpm)。其中,组 0 有 556 名患者(50%),组 1 有 196 名(18%),组 2 有 350 名(32%)。在组 1 中,平均 θ 为 1240 ± 410 mL·min(580-2560 mL·min),75% ± 8%V˙O(52%-92%V˙O)或 84% ± 6%HR(64%-96%HR)。在组 2 中,θ 为 1390 ± 360 mL·min(640-2430 mL·min),70% ± 8%V˙O(41%-88%V˙O)或 78% ± 7%HR(52%-96%HR),RCP 为 1680 ± 440 mL·min(730-3090 mL·min),84% ± 7%V˙O(54%-99%V˙O)或 87% ± 6%HR(59%-99%HR)。与组 1 相比,组 2 中的 θ 发生在更高的 V˙O 但更低的 %V˙O 和 %HR(P < 0.05)。

结论

尽管协议选项具有灵活性,但只有 32%的 CPET 同时显示出 θ 和 RCP。常用的基于步长的方案不适合“基于阈值”的运动处方。

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