傅里叶变换红外光谱技术在脓肿分枝杆菌复合群亚种分化中的应用。
Application of FT-IR Spectroscopy for Mycobacterium abscessus complex subspecies differentiation.
机构信息
Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy; Department of Public Health and Paediatrics, University of Turin, Turin, Italy.
Bruker Daltonics GmbH & Co. KG, Bremen, Germany.
出版信息
J Microbiol Methods. 2023 Sep;212:106792. doi: 10.1016/j.mimet.2023.106792. Epub 2023 Jul 28.
Mycobacterium abscessus complex (MABSC) subspecies differentiation improves patients' therapy and outcome. Fourier-Transform-Infrared Spectroscopy (FT-IRS) was applied for subspecies discrimination of 15 strains on different media: Löwenstein-Jensen showed the best resolution power; Linear Discriminant Analysis model differentiated M. abscessus susbsp. abscessus from M. abscessus subsp. massiliense. FT-IRS has a potential role in rapidly MABSC subspecies identification.
脓肿分枝杆菌复合体（MABSC）亚种分化可改善患者的治疗效果和预后。傅里叶变换红外光谱（FT-IRS）技术已应用于不同培养基上的 15 株菌的亚种鉴别： Löwenstein-Jensen 培养基具有最佳分辨率；线性判别分析模型可区分脓肿分枝杆菌亚种和马萨诸塞分枝杆菌亚种。FT-IRS 可能有助于快速鉴定 MABSC 亚种。
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