Kobayashi M, Imai K, Kiren H, Ito Y, Yamanaka H
Hinyokika Kiyo. 1986 May;32(5):721-8.
A case of asynchronous bilateral renal cell carcinoma is reported. The patient was a 71-year-old man who visited our clinic with complaints of asymptomatic macrohematuria and fever on November 20, 1960. Clinical diagnosis was left renal tumor and left nephrectomy was performed on December 4, 1960. Histological diagnosis was renal cell carcinoma (common type, clear cell subtype, alveolar type and G1). The postoperative course was uneventful until complaints of diarrhea and weight loss in November, 1983. He visited our clinic again with a right abdominal mass on January, 1984. Right renal selective angiography revealed an enlargement and abnormal vascularity with tumor stain, hypervascularity and pooling in the whole kidney except for the upper pole lesion. CT scan revealed a space occupying lesion. Right radical nephrectomy was performed on March 6, 1984. Histological diagnosis was renal cell carcinoma (common type, mixed subtype, alveolar and tubular type, G2). He was treated by hemodialysis and steroid therapy after right nephrectomy but he died of massive gastro-intestinal bleeding on April 22, 1984. The paper is the 15th report of a bilateral renal cell carcinoma in Japan.
报告一例异时性双侧肾细胞癌病例。患者为一名71岁男性，于1960年11月20日因无症状肉眼血尿和发热前来我院就诊。临床诊断为左肾肿瘤，并于1960年12月4日行左肾切除术。组织学诊断为肾细胞癌（普通型、透明细胞亚型、肺泡型，G1级）。术后直至1983年11月出现腹泻和体重减轻症状前，病情平稳。1984年1月，他因右侧腹部肿块再次来我院就诊。右侧肾选择性血管造影显示右肾增大，血管异常，有肿瘤染色，除肾上极病变外，全肾血管增多且有造影剂潴留。CT扫描显示有占位性病变。1984年3月6日行右侧根治性肾切除术。组织学诊断为肾细胞癌（普通型、混合亚型、肺泡和管状型，G2级）。右侧肾切除术后，他接受了血液透析和类固醇治疗，但于1984年4月22日死于大量胃肠道出血。本文是日本第15例双侧肾细胞癌报告。
