Hayat M, Bayssas M, Brulé G, Cappelaere P, Cattan A, Chauvergne J, Clavel B, Gouveia J, Guerrin J, Pommatau E, Muggia F, Mathé G
Nouv Presse Med. 1979 Mar 31;8(15):1231-4.
We have conducted a phase II trial of cisdiammino-dichloro platinum (CDDP) which demonstrates its remarkable activity in testis embryonic carcinoma, in ovary carcinoma and in epidermoid cancers, especially head and neck and uterus cervix carcinoma. Its toxicity in mainly digestive and renal. This compound is now indicated in combinations in the case of the above mentioned tumors.
我们进行了一项顺二氨二氯铂(CDDP)的II期试验,该试验表明其在睾丸胚胎癌、卵巢癌和表皮样癌,尤其是头颈癌和子宫颈癌中具有显著活性。其毒性主要在消化系统和肾脏。这种化合物目前适用于上述肿瘤的联合治疗。