Perry S B, Lang P, Keane J F, Jonas R A, Sanders S P, Lock J E
Am J Cardiol. 1986 Sep 15;58(7):622-6. doi: 10.1016/0002-9149(86)90288-2.
Patients with left atrioventricular (AV) valve atresia or stenosis were studied retrospectively to determine the incidence of early and late failures of procedures to enlarge an interatrial communication. The 61 patients underwent 80 procedures: 5 balloon atrial septostomies, 12 blade atrial septostomies and 63 surgical septectomies. No balloon septostomy provided adequate long-term palliation. Of 12 blade septostomies, 4 resulted in gradients across the atrial septum of 5 to 8 mm Hg and 8 in gradients 3 mm Hg or less. Results from blade septostomy were unrelated to underlying diagnosis, age, gradient before the procedure, number of previous procedures, pulmonary blood flow or size of the postprocedure defect by balloon sizing, but were related to size of the postoperative defect estimated by echocardiography. Among 8 patients with gradients of 3 mm Hg or less after blade septostomy, 7 were followed 9 +/- 7 months and showed no evidence of restenosis. Of 63 surgical septectomies, 11 (17.5%) were inadequate, and in at least 7 cases the failure was due to restenosis of the defect as documented by serial catheterizations or echocardiograms. Outcome after surgical septectomy was unrelated to underlying diagnosis, age or number of previous procedures, but was related to size of the defect created. Our results reveal improved results in terms of residual gradient for blade septostomy compared with previous studies and the need to follow these patients carefully, even those undergoing surgical septectomy.
对患有左房室(AV)瓣闭锁或狭窄的患者进行了回顾性研究,以确定扩大房间隔交通的手术早期和晚期失败的发生率。61例患者接受了80次手术:5次球囊房间隔造口术、12次刀片式房间隔造口术和63次外科房间隔切除术。没有球囊房间隔造口术能提供足够的长期姑息治疗。在12次刀片式房间隔造口术中,4次导致房间隔压差为5至8mmHg,8次压差为3mmHg或更低。刀片式房间隔造口术的结果与潜在诊断、年龄、手术前压差、既往手术次数、肺血流量或球囊测量的术后缺损大小无关,但与超声心动图估计的术后缺损大小有关。在刀片式房间隔造口术后压差为3mmHg或更低的8例患者中,7例随访9±7个月,未显示再狭窄迹象。在63次外科房间隔切除术中,11次(17.5%)不充分,至少7例失败是由于缺损再狭窄,经系列心导管检查或超声心动图证实。外科房间隔切除术后的结果与潜在诊断、年龄或既往手术次数无关,但与所造成缺损的大小有关。我们的结果显示,与先前研究相比,刀片式房间隔造口术在残余压差方面有改善,并且需要仔细随访这些患者,即使是接受外科房间隔切除术的患者。