Flores A D, Dickson R I, Riding K, Coy P
Am J Clin Oncol. 1986 Aug;9(4):281-91. doi: 10.1097/00000421-198608000-00002.
The Chinese population in British Columbia has been increasing in recent years due to the migration of the Chinese from Southern China, which has tripled during the last decade. From 1939 to 1980, 296 cases of nasopharyngeal carcinoma (NPC) were seen at the Cancer Control Agency of British Columbia (CCABC). Of these, 167 (56%) were Chinese and 119 (40%) were Caucasians. The incidence of cancer of the nasopharynx in the Chinese born in China was 115 times greater than Caucasians before 1970 and 107 times greater in the 1970s. The incidence of NPC in the Caucasian population remained unchanged as did that of the North American-born Chinese (six times greater than that of the Caucasians) for the last 2 decades. The overall survival for all cases was 39% at 5 years and 28% at 10 years. The survival of cases was better in patients treated after 1970 (48% at 5 years and 36% at 10 years) than in patients treated before 1970 (34% at 5 years and 20% at 10 years). The survival was 50% at 5 years for all N0 cases but it was only 27% in patients with nodal metastasis. The survival of NPC was related essentially to initial staging, type and dose of irradiation, and pre-irradiation biopsy of neck metastasis. The survival was not significantly related to birth place, race, or histological grade.
近年来，由于中国南方人口的迁移，不列颠哥伦比亚省的华裔人口一直在增加，在过去十年中增加了两倍。1939年至1980年期间，不列颠哥伦比亚癌症控制局（CCABC）共诊治了296例鼻咽癌（NPC）患者。其中，167例（56%）为华裔，119例（40%）为白种人。1970年前，在中国出生的华裔鼻咽癌发病率比白种人高115倍，20世纪70年代高107倍。在过去20年中，白种人群体中的NPC发病率以及北美出生的华裔（比白种人高6倍）的发病率均保持不变。所有病例的5年总生存率为39%，10年总生存率为28%。1970年后接受治疗的患者生存率（5年生存率为48%，10年生存率为36%）高于1970年前接受治疗的患者（5年生存率为34%，10年生存率为20%）。所有N0期病例的5年生存率为50%，但有淋巴结转移的患者5年生存率仅为27%。NPC的生存率主要与初始分期、放疗类型和剂量以及颈部转移灶放疗前活检有关。生存率与出生地、种族或组织学分级无显著相关性。
