Farrokhnia Farrokh, Derakhshan Ali, Fallahzade Mohammadhossein, Basiratnia Mitra
Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Caspian J Intern Med. 2023 Summer;14(3):454-459. doi: 10.22088/cjim.14.3.454.
Idiopathic nephrotic syndrome (INS) is one of the chronic diseases in children and it is important to identify its related factors. The present study aimed at investigating the relationship between infection and the incidence and recurrence of idiopathic nephrotic syndrome in children.
The total number of case participants was 40 and the total number of control participants was 41. Based on the number of cases of nephrotic syndrome (NS), the same number of healthy children of the same age and gender were selected as the control group. The information and data collected include demographic characteristics of patients, duration of disease, number of recurrences, blood pressure and blood excretion in urine, height, and weight, and presence of gastrointestinal symptoms on the checklist. The data were entered into SPSS and analyzed at a significance level of 05.
From 81 participants in the study, 11 (13.75%) cases were positive, of whom 7 (17.5%) cases were in the control group and 4 (10%) cases were in the patients' group. There was no significant difference between the two groups in terms of infection rate (P = 0.863). Moreover, there were no significant differences between the patients suffering from the nephrotic syndrome in terms of height, weight, blood pressure, hematuria, duration and recurrence of the disease (p>0.05).
According to the evaluations performed in the present study, there was no relationship between low birth weight, blood pressure, disease duration, and disease recurrence with NS.
特发性肾病综合征（INS）是儿童慢性疾病之一，识别其相关因素很重要。本研究旨在调查感染与儿童特发性肾病综合征的发病率和复发之间的关系。
病例参与者总数为40例，对照参与者总数为41例。根据肾病综合征（NS）病例数，选择相同数量的年龄和性别相同的健康儿童作为对照组。收集的信息和数据包括患者的人口统计学特征、病程、复发次数、血压和尿排泄情况、身高和体重，以及清单上胃肠道症状的存在情况。数据录入SPSS并在显著性水平0.05下进行分析。
在该研究的81名参与者中，11例（13.75%）呈阳性，其中对照组7例（17.5%），患者组4例（10%）。两组之间的感染率无显著差异（P = 0.863）。此外，肾病综合征患者在身高、体重、血压、血尿、病程和疾病复发方面也无显著差异（p>0.05）。
根据本研究进行的评估，低出生体重、血压、病程和疾病复发与NS之间没有关系。
