Sivakumar Brahman Shankar, Gia An Vincent Vin, Stewart Nicholas, Manoharan Shobhan, Graham David
Department of Hand Surgery, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Department of Orthopaedic Surgery, Royal North Shore Hospital, New South Wales, Australia 2065.
J Hand Surg Glob Online. 2023 May 2;5(4):459-462. doi: 10.1016/j.jhsg.2022.10.018. eCollection 2023 Jul.
Alkaptonuria is a rare metabolic disorder characterized by the accumulation of homogentisic acid. Its effects on the central nervous system are well-recognized; however, cases of pathologic homogentisic acid deposition in the peripheral nervous system are less well-described. We report the case of a 72-year-old man with a prior history of alkaptonuria presenting with bilateral carpal tunnel and left-sided cubital tunnel symptoms. This case is of note because the patient demonstrated a rapid onset of symptoms due to pathology at multiple foci.
黑尿症是一种罕见的代谢紊乱疾病，其特征是尿黑酸的积累。它对中枢神经系统的影响已得到充分认识；然而，关于尿黑酸在外周神经系统中病理性沉积的病例描述较少。我们报告了一例72岁男性患者，既往有黑尿症病史，出现双侧腕管综合征和左侧肘管综合征症状。该病例值得关注，因为患者因多个病灶的病变而症状迅速出现。
