Department of Obstetrics & Gynecology, DY Patil Medical College, DY Patil Education Society (Deemed to be University), Kolhapur, Kasaba Bawada, Maharashtra, 416006, India.
Department of Stem Cell and Regenerative Medicine, Center for Interdisciplinary Research, DY Patil Education Society (Deemed to be University), Kolhapur, Kasaba Bawada, Maharashtra, 416006, India.
Future Microbiol. 2023 Jul;18:673-679. doi: 10.2217/fmb-2022-0251. Epub 2023 Jul 31.
Cruciferous vegetables and mustard oil are rich in the glucosinolate group of molecules. Isothiocyanates are an important group of glucosinolate derivatives. These derivatives have various bioactive properties, including antioxidant, antibacterial, anticarcinogenic, antifungal, antiparasitic, herbicidal and antimutagenic activity. Previous studies indicate that regular intake of such vegetables may considerably reduce the incidence of various types of cancer. These studies have inspired studies where the bioactive agents of these plants have been isolated and explored for their therapeutic applications. The use of these bioactive compounds as antifungals could be a new therapeutic approach against human pathogenic fungi. Isothiocyanates have been studied for their antifungal activity and have the potential to be used for antifungal therapy.
十字花科蔬菜和芥子油富含硫代葡萄糖苷类分子。异硫氰酸酯是硫代葡萄糖苷的重要衍生物之一。这些衍生物具有多种生物活性，包括抗氧化、抗菌、抗癌、抗真菌、抗寄生虫、除草和抗突变活性。先前的研究表明，经常食用这些蔬菜可以显著降低各种癌症的发病率。这些研究激发了对这些植物的生物活性物质进行分离并探索其治疗应用的研究。将这些生物活性化合物用作抗真菌药物可能是对抗人体致病真菌的一种新的治疗方法。异硫氰酸酯的抗真菌活性已得到研究，具有用于抗真菌治疗的潜力。
