Carlino Mauro, Uretsky Barry F, Azzalini Lorenzo, Nascimbene Angelo, Brilakis Emmanouil S, Colombo Antonio, Nakamura Sunao, Godino Cosmo, Avran Alexandre, Rinfret Stéphane, Faurie Benjamin
Cardio-Thoracic-Vascular Department, Interventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Central Arkansas Veterans Health System, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Catheter Cardiovasc Interv. 2023 Oct;102(4):577-584. doi: 10.1002/ccd.30789. Epub 2023 Jul 31.
Antegrade dissection and re-entry (ADR) is an integral part of the hybrid algorithm, which has allowed for improved outcomes in chronic total occlusion (CTO) coronary intervention (PCI).
A new ADR method, Subintimal Antegrade FEnestration and Re-entry (SAFER), is described. The results of a first-in-man series are presented.
SAFER was performed on seven consecutive patients with angiographic and clinical success in all patients.
This first-in-man study has shown that the SAFER technique is feasible and effective with the possibility of improving the antegrade PCI CTO success rate.
顺行夹层分离及再入路（ADR）是杂交技术的一个组成部分，该技术已使慢性完全闭塞（CTO）冠状动脉介入治疗（PCI）的疗效得到改善。
描述了一种新的ADR方法，即内膜下顺行开窗及再入路（SAFER）。介绍了首例人体研究系列的结果。
对连续7例患者实施了SAFER，所有患者均获得血管造影及临床成功。
这项首例人体研究表明，SAFER技术可行且有效，有可能提高CTO顺行PCI成功率。
