Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium.
Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; Center for Plant Systems Biology, VIB, 9052 Ghent, Belgium.
Curr Opin Plant Biol. 2023 Oct;75:102429. doi: 10.1016/j.pbi.2023.102429. Epub 2023 Jul 29.
The plasma membrane (PM) houses a wide variety of proteins, facilitating interactions between the cell and its surroundings. Perception of external stimuli leads to selective internalization of membrane proteins via endocytosis. A multitude of endocytic signals affect protein internalization; however, their coordination and the exact mechanism of their recognition still remain elusive. In this review, we summarized the up-to-date knowledge of different internalization signals in PM cargo proteins and their involvement during protein trafficking.
质膜（PM）含有多种蛋白质，促进细胞与其周围环境之间的相互作用。对外界刺激的感知会导致通过内吞作用选择性地内化膜蛋白。许多内吞作用信号会影响蛋白质的内化；然而，它们的协调和确切的识别机制仍然难以捉摸。在这篇综述中，我们总结了 PM 货物蛋白中不同内化信号的最新知识及其在蛋白质运输过程中的参与情况。
