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评价致病变种大肠杆菌致实验性猪尿路感染的尿液试纸检测。

Evaluation of urine dipstick tests in experimental porcine urinary tract infection with uropathogenic Escherichia coli.

机构信息

Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark.

Research Unit of Clinical Microbiology, University of Southern Denmark, Odense, Denmark.

出版信息

Sci Rep. 2023 Jul 31;13(1):12404. doi: 10.1038/s41598-023-39239-7.

Abstract

Urinary tract infection is a common disease in pigs and a major reason for sows to be culled. The disease, however, is difficult to diagnose due to lack of distinct clinical signs in the animals. We evaluated the diagnostic value of two commercial urine dipstick tests in 10 pigs using an experimental model of Escherichia coli urinary tract infection. Urine collected at baseline and 48 h after inoculation were analyzed. We show that dipstick tests positive of blood, leucocytes and particularly nitrite are very specific for E. coli UTI with a 100% positive predictive value.

摘要

尿路感染是猪的常见病,也是母猪淘汰的主要原因。然而,由于动物缺乏明显的临床症状,因此该病难以诊断。我们使用大肠杆菌尿路感染的实验模型评估了两种商业尿液试纸检测在 10 头猪中的诊断价值。分析了基线和接种后 48 小时采集的尿液。我们表明,尿液试纸检测血液、白细胞和特别是亚硝酸盐阳性对大肠杆菌尿路感染具有非常高的特异性,阳性预测值为 100%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9acc/10390499/1369d46283b7/41598_2023_39239_Fig1_HTML.jpg

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