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优化先天性心脏病患儿结局的营养策略。

Nutritional Strategies to Optimize Outcomes among Infants with Congenital Heart Disease.

机构信息

Division of Neonatology, Department of Pediatrics, Ohio State University, Nationwide Children's Hospital, Columbus, OH.

Ohio State University, Columbus, OH.

出版信息

Neoreviews. 2023 Aug 1;24(8):e492-e503. doi: 10.1542/neo.24-8-e492.

Abstract

Growth failure is common among infants with congenital heart disease (CHD), affecting approximately half of all infants with CHD. Achieving good growth is difficult secondary to both cardiac and noncardiac factors that affect energy expenditure and nutritional intake. Growth failure is associated with poor outcomes, including mortality, prolonged length of hospital stay, delayed cardiac surgery, postoperative complications, and neurodevelopmental delay. Clinical practice varies widely when it comes to how nutrition is managed in these infants, with varying approaches to enteral feeding initiation, advancement, and discontinuation. This variation persists despite several practice guidelines that have been created in recent years to guide nutritional care. Standardized feeding protocols have been proven to reduce growth failure and improve outcomes for this patient population. Centers and clinicians should be encouraged to adopt existing guidelines, or create their own from evidence-based literature, to improve growth and outcomes for infants with CHD.

摘要

生长发育迟缓在先天性心脏病(CHD)患儿中很常见,大约影响所有 CHD 患儿的一半。由于影响能量消耗和营养摄入的心脏和非心脏因素,实现良好的生长发育很困难。生长发育迟缓与不良预后相关,包括死亡率、住院时间延长、心脏手术延迟、术后并发症和神经发育迟缓。在这些患儿中如何管理营养方面,临床实践差异很大,肠内喂养的启动、推进和停止方式也各不相同。尽管近年来制定了多项实践指南来指导营养护理,但这种差异仍然存在。标准化喂养方案已被证明可减少生长发育迟缓,并改善该患者人群的预后。应鼓励中心和临床医生采用现有的指南,或根据循证文献制定自己的指南,以改善 CHD 患儿的生长和预后。

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