Candura Dario, Ciolli Gianluca, Chiriacò Federico, Cianni Luigi, Marescalchi Marina, Brancaccio Vincenzo, Corona Katia, Santagada Domenico Alessandro, Maccauro Giulio, Cerciello Simone
Department of Orthopaedics and Traumatology, Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy.
AO Ordine Mauriziano, Orthopaedics and Traumatology Department - University of Turin, Largo Turati 62, 10128, Turin, Italy.
Orthop Rev (Pavia). 2023 Jul 28;15:84277. doi: 10.52965/001c.84277. eCollection 2023.
To evaluate the clinical and functional outcomes of meniscal allograft transplantation (MAT) with anterior cruciate ligament reconstruction (ACLR) in a single surgical stage through a systematic review of the currently available evidence.
A systematic search of the PubMed and Google Scholar databases, with no publication date limit, until December 2022 was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Follow-up studies and case series published in English involving patients undergoing a combination of ACLR and MAT were included. The quality of these studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS) checklist. A systematic review of the International Knee Documentation Committee (IKDC), Lysholm and Tegner activity scores was conducted.
Seven studies involving 154 patients were included. The mean follow-up was 5,3 years. The mean age at the time of the surgery was of 35.3 years. All studies used the Lysholm Knee score, IKDC score or Tegner activity score to measure clinical outcomes post-operatively and the mean improvements were 26.7, 24.7, and 1.8 respectively. The rate to return to sport was 75.5 %. No intra-operative complications were reported. The post-operative complication rate was 11.6%.
MAT combined with ACLR procedure showed good clinical results up to an average of 5 years of follow-up. More studies need to be conducted that can better understand the long-term effects of this combined procedure.
通过对现有证据进行系统评价，评估在单一手术阶段进行半月板同种异体移植（MAT）联合前交叉韧带重建（ACLR）的临床和功能结果。
按照系统评价和Meta分析的首选报告项目（PRISMA），对PubMed和谷歌学术数据库进行系统检索，检索截至2022年12月且无出版日期限制的文献。纳入以英文发表的涉及接受ACLR和MAT联合手术患者的随访研究和病例系列。使用非随机研究方法学指数（MINORS）清单评估这些研究的质量。对国际膝关节文献委员会（IKDC）、Lysholm和Tegner活动评分进行系统评价。
纳入7项研究，共154例患者。平均随访时间为5.3年。手术时的平均年龄为35.3岁。所有研究均使用Lysholm膝关节评分、IKDC评分或Tegner活动评分来测量术后临床结果，平均改善分别为26.7、24.7和1.8。恢复运动的比例为75.5%。未报告术中并发症。术后并发症发生率为11.6%。
MAT联合ACLR手术在平均5年的随访期内显示出良好的临床效果。需要开展更多研究，以更好地了解这种联合手术的长期效果。
