Shiraishi Koji
Department of Urology, Yamaguchi University School of Medicine, Yamaguchi, Japan.
Int J Urol. 2023 Nov;30(11):959-967. doi: 10.1111/iju.15264. Epub 2023 Aug 1.
Longevity with localized prostate cancer (PCa) has been achieved, and the contribution of robot-assisted radical prostatectomy (RARP) to cancer control is evident. The next step to investigate in the treatment of localized PCa is improvement of the quality of life (QOL) after RARP. Erectile dysfunction has been considered a major surgical complication, and patient satisfaction after RARP has not improved despite the development of nerve preservation and penile rehabilitation. To comprehensively understand sexual dysfunction after RARP, we must investigate other complications with regard to sexual health, including low sexual desire, disturbed orgasmic function (i.e., anejaculation, orgasm intensity, painful orgasm, and climacturia), shortening of penile length, penile curvature (Peyronie's disease) and unique psychological alterations after the diagnosis of PCa, which are neglected side effects after prostatectomy. In this context, routine evaluation of erectile function by the International Index of Erectile Function only is not sufficient to understand patients' difficulties. A questionnaire is just one way of enabling patients to evaluate their pre- and postoperative concerns; listening to patients face-to-face is warranted to detect symptoms. Understanding the relationship between symptoms and preserved nerve localization can ultimately provide an individualized nerve-sparing procedure and improve patient satisfaction after RARP. In combination with psychological counseling, including the partner and medical treatment, such as testosterone replacement, it is time to reconsider ways to improve sexual dysfunction after RARP.
局限性前列腺癌(PCa)患者已实现长期生存,机器人辅助根治性前列腺切除术(RARP)对癌症控制的贡献显著。在局限性PCa治疗中,下一步要研究的是RARP术后生活质量(QOL)的改善。勃起功能障碍一直被视为主要的手术并发症,尽管在神经保留和阴茎康复方面取得了进展,但RARP术后患者的满意度并未提高。为全面了解RARP术后的性功能障碍,我们必须研究与性健康相关的其他并发症,包括性欲低下、性高潮功能障碍(即不射精、性高潮强度、性高潮疼痛和遗尿)、阴茎长度缩短、阴茎弯曲(佩罗尼氏病)以及PCa诊断后的独特心理变化,这些都是前列腺切除术后被忽视的副作用。在此背景下,仅通过国际勃起功能指数对勃起功能进行常规评估不足以了解患者的困难。问卷调查只是让患者评估其术前和术后担忧的一种方式;有必要与患者面对面交流以发现症状。了解症状与保留神经定位之间的关系最终可提供个体化的神经保留手术,并提高RARP术后患者的满意度。结合包括伴侣参与的心理咨询和睾酮替代等医学治疗,是时候重新考虑改善RARP术后性功能障碍的方法了。