Obstetrics & Gynecology, Centre for Ultrasound and Prenatal Medicine, Frankfurt, Germany.
Institut für Klinische Genetik Nordrhein, Labor Eiben Glaubitz, Essen, Germany.
Ultraschall Med. 2023 Dec;44(6):600-605. doi: 10.1055/a-2104-2689. Epub 2023 Aug 1.
Combined first-trimester screening (FTS) and noninvasive prenatal testing (NIPT) have been proven to be reliable noninvasive procedures to detect the most common chromosomal abnormalities (trisomies 21, 18, 13) in the first trimester. The aim of this paper is to demonstrate the strengths and limitations of these two procedures and to give a consensus statement of the Fetal Medicine Foundation (FMF) Germany on how to use the two techniques in the first trimester after the introduction of NIPT as a service of the statutory health insurance companies in Germany.
联合早孕期筛查（FTS）和无创性产前检测（NIPT）已被证明是可靠的非侵入性方法，可在早孕期检测最常见的染色体异常（三体 21、18、13）。本文旨在展示这两种方法的优缺点，并在德国强制性健康保险引入 NIPT 服务后，就如何在早孕期使用这两种技术，为德国胎儿医学基金会（FMF）提供一个共识声明。
