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SARS-CoV-2 - No Increased Islet Autoimmunity or Type 1 Diabetes in Teens.新型冠状病毒 - 青少年胰岛自身免疫或1型糖尿病未增加
N Engl J Med. 2023 Aug 3;389(5):474-475. doi: 10.1056/NEJMc2216477.
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SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood.SARS-CoV-2 感染与儿童早期胰岛自身免疫的发展。
JAMA. 2023 Sep 26;330(12):1151-1160. doi: 10.1001/jama.2023.16348.
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The evaluation of pancreas β-cell autoantibodies in non-diabetic COVID-19 patients.非糖尿病 COVID-19 患者胰腺 β 细胞自身抗体的评估。
Arch Endocrinol Metab. 2022;66(4):459-465. doi: 10.20945/2359-3997000000498. Epub 2022 Jun 2.
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Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes.儿童早期体重指数及其与 COVID-19 大流行、防控措施和 1 型糖尿病高危儿童胰岛自身免疫的关系。
Diabetologia. 2024 Apr;67(4):670-678. doi: 10.1007/s00125-023-06079-z. Epub 2024 Jan 12.
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No effects of COVID-19 on the development of type 1 diabetes autoimmunity and no evidence of an increased frequency of SARS-CoV-2 antibodies in newly diagnosed type 1 diabetes patients relative to healthy subjects.未发现 COVID-19 对 1 型糖尿病自身免疫发展的影响，也未发现新诊断的 1 型糖尿病患者相对于健康受试者 SARS-CoV-2 抗体的频率增加。
Acta Diabetol. 2023 Oct;60(10):1301-1307. doi: 10.1007/s00592-023-02103-1. Epub 2023 May 12.
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Physical activity and progression to type 1 diabetes in children and youth with islet autoimmunity: The diabetes autoimmunity study in the young.身体活动与胰岛自身免疫的儿童和青少年进展为 1 型糖尿病：年轻糖尿病自身免疫研究。
Pediatr Diabetes. 2022 Jun;23(4):462-468. doi: 10.1111/pedi.13323. Epub 2022 Mar 7.
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Late-onset islet autoimmunity in childhood: the Diabetes Autoimmunity Study in the Young (DAISY).儿童期迟发性胰岛自身免疫：青少年糖尿病自身免疫研究（DAISY）
Diabetologia. 2017 Jun;60(6):998-1006. doi: 10.1007/s00125-017-4256-9. Epub 2017 Mar 17.
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Risk of celiac disease, type 1 diabetes, and thyroid disease autoimmunity during the SARS-CoV-2 pandemic in South of Sweden: insights from the TRIAD study.瑞典南部新冠疫情期间乳糜泻、1型糖尿病和自身免疫性甲状腺疾病的风险：来自TRIAD研究的见解
Autoimmunity. 2025 Dec;58(1):2490491. doi: 10.1080/08916934.2025.2490491. Epub 2025 Apr 15.
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COVID-19 as a Trigger for Type 1 Diabetes.COVID-19 作为 1 型糖尿病的诱因。
J Clin Endocrinol Metab. 2023 Aug 18;108(9):2176-2183. doi: 10.1210/clinem/dgad165.
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Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report.感染 SARS-CoV-2 后出现的自身抗体阴性胰岛素依赖型糖尿病：一例报告。
Nat Metab. 2020 Oct;2(10):1021-1024. doi: 10.1038/s42255-020-00281-8. Epub 2020 Sep 2.
引用本文的文献
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Increased Risk of Type 1 Diabetes in Boys Under the Age of 5 Years During COVID-19 Lockdowns in Finland, Sweden and Stanford, CA, USA-An Observational Multicenter Study.芬兰、瑞典及美国加利福尼亚州斯坦福市新冠疫情封锁期间5岁以下男童1型糖尿病风险增加——一项多中心观察性研究
Diabetes Metab Res Rev. 2025 Sep;41(6):e70084. doi: 10.1002/dmrr.70084.
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Respiratory infections in pregnancy and early life-association with the development of islet autoimmunity and type 1 diabetes in children: systematic review and meta-analysis of observational studies.孕期及生命早期的呼吸道感染与儿童胰岛自身免疫及1型糖尿病发生的关联：观察性研究的系统评价与荟萃分析
EClinicalMedicine. 2025 Jul 10;85:103324. doi: 10.1016/j.eclinm.2025.103324. eCollection 2025 Jul.
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SARS-CoV-2 infection and new-onset type 1 diabetes in the post-acute period among children and young people in England.英国儿童和青少年急性后期的新冠病毒2型感染与新发1型糖尿病
Diabet Med. 2025 Sep;42(9):e70084. doi: 10.1111/dme.70084. Epub 2025 Jun 17.
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Remission Period in Children With Newly Diagnosed Type 1 Diabetes During the COVID-19 Pandemic-Results From the DPV Registry.新冠疫情期间新诊断1型糖尿病儿童的缓解期——来自糖尿病数据与实践注册研究的结果
Pediatr Diabetes. 2025 May 15;2025:9903467. doi: 10.1155/pedi/9903467. eCollection 2025.
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Increase in new-onset type 1 diabetes diagnoses among Brazilian children and adolescents during the COVID-19 pandemic.新冠疫情期间巴西儿童和青少年中新发1型糖尿病诊断病例数增加。
J Pediatr (Rio J). 2025 Jul-Aug;101(4):651-656. doi: 10.1016/j.jped.2025.04.001. Epub 2025 May 29.
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Restoration of intestinal secondary bile acid synthesis: A potential approach to improve pancreatic β cell function in type 1 diabetes.恢复肠道次级胆汁酸合成：改善1型糖尿病患者胰腺β细胞功能的一种潜在方法。
Cell Rep Med. 2025 May 20;6(5):102130. doi: 10.1016/j.xcrm.2025.102130. Epub 2025 May 9.
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Unfolding the Mystery of Autoimmunity: The Environmental Determinants of Diabetes in the Young (TEDDY) Study.揭开自身免疫之谜：青少年糖尿病的环境决定因素（TEDDY）研究
Diabetes Care. 2025 Jul 1;48(7):1125-1135. doi: 10.2337/dc24-2886.
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SARS-CoV-2 Infection and Childhood Islet Autoimmunity.严重急性呼吸综合征冠状病毒2感染与儿童胰岛自身免疫
JAMA Pediatr. 2025 May 1;179(5):568-570. doi: 10.1001/jamapediatrics.2024.6848.
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Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol.针对1型糖尿病自身免疫的抗病毒作用：GPPAD-AVAnT1A研究方案。
Contemp Clin Trials Commun. 2025 Jan 20;44:101434. doi: 10.1016/j.conctc.2025.101434. eCollection 2025 Apr.
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New-Onset Type 1 and Type 2 Diabetes Among Korean Youths During the COVID-19 Pandemic.新冠疫情期间韩国青少年新发1型和2型糖尿病情况
JAMA Pediatr. 2025 Feb 1;179(2):155-162. doi: 10.1001/jamapediatrics.2024.5068.
本文引用的文献
1
Association of SARS-CoV-2 Infection With New-Onset Type 1 Diabetes Among Pediatric Patients From 2020 to 2021.2020 年至 2021 年 SARS-CoV-2 感染与儿童新发 1 型糖尿病的相关性。
JAMA Netw Open. 2022 Sep 1;5(9):e2233014. doi: 10.1001/jamanetworkopen.2022.33014.
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Increase in newly diagnosed type 1 diabetes in youth during the COVID-19 pandemic in the United States: A multi-center analysis.美国 COVID-19 大流行期间青少年新发 1 型糖尿病的增加：一项多中心分析。
Pediatr Diabetes. 2022 Jun;23(4):433-438. doi: 10.1111/pedi.13328. Epub 2022 Mar 16.
3
Incidence of New-Onset Type 1 Diabetes Among US Children During the COVID-19 Global Pandemic.新冠大流行期间美国儿童新发 1 型糖尿病的发病率。
JAMA Pediatr. 2022 Apr 1;176(4):414-415. doi: 10.1001/jamapediatrics.2021.5801.
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Risk for Newly Diagnosed Diabetes >30 Days After SARS-CoV-2 Infection Among Persons Aged <18 Years - United States, March 1, 2020-June 28, 2021.2020 年 3 月 1 日至 2021 年 6 月 28 日期间，年龄<18 岁的 SARS-CoV-2 感染者在新冠病毒感染后 30 天以上新发糖尿病的风险。
MMWR Morb Mortal Wkly Rep. 2022 Jan 14;71(2):59-65. doi: 10.15585/mmwr.mm7102e2.
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The Environmental Determinants of Diabetes in the Young (TEDDY) study: study design.青少年糖尿病环境决定因素（TEDDY）研究：研究设计
Pediatr Diabetes. 2007 Oct;8(5):286-98. doi: 10.1111/j.1399-5448.2007.00269.x.
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