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澳大利亚痴呆症患病率的变化及其与地理偏远程度的关系。

Changes in the prevalence of dementia in Australia and its association with geographic remoteness.

机构信息

Department of Economics, American International University-Bangladesh (AIUB), Dhaka, Bangladesh.

School of Business, University of Southern Queensland, Toowoomba, Queensland, Australia.

出版信息

PLoS One. 2023 Aug 2;18(8):e0289505. doi: 10.1371/journal.pone.0289505. eCollection 2023.

Abstract

BACKGROUND

The exact prevalence of dementia in Australia is ambiguous. Australia is a vast continent with a small population, and 80% of the population live in five cities. This study explores recent changes in the prevalence of dementia. It also investigates geographic remoteness as a potential risk factor for developing dementia.

METHODS

Survey of Disability, Ageing and Carers (SDAC), a nationally representative database, was used to conduct this study. A total of 74,862 and 65,487 individuals from 2015 and 2018, respectively, were considered for this study. A multivariable logistic regression model was used to evaluate the association between dementia and geographic remoteness for older adults aged 65 years and over.

RESULTS

The results reveal that from 2015 to 2018, the prevalence of dementia among adults aged 65 years and older was higher in 2018 (5,229 per 100,000) than in 2015 (5,099 per 100,000). Significant geographical differences in the prevalence of dementia are observed among Australian adults, and this trend appears to be increasing. Furthermore, the unadjusted model revealed that, in 2015, older adults living in major cities had 1.29 (AOR: 1.29, 95% CI: 1.17-1.41) times higher odds of having dementia compared with their counterparts from outer regional and remote areas. In 2018, the adjusted model found that older adults living in major cities had 1.12 (AOR: 1.12, 95% CI: 1.01-1.25) times elevated odds of having dementia than their peers living in outer regional and remote areas.

CONCLUSION

There is a rising prevalence of dementia in Australia. Further investigation is required to identify the causes of this increase. Increased public health initiatives should concentrate on behavioural characteristics and contextual environmental factors to ameliorate this trend.

摘要

背景

澳大利亚痴呆症的确切患病率并不明确。澳大利亚是一个幅员辽阔的大陆,人口稀少,80%的人口居住在五个城市。本研究探讨了痴呆症患病率的近期变化。它还研究了地理位置偏远是否是患痴呆症的潜在风险因素。

方法

本研究使用全国代表性数据库残疾、老龄化和照顾者调查(SDAC)进行。共纳入了 2015 年和 2018 年分别为 74862 人和 65487 人。对年龄在 65 岁及以上的老年人,采用多变量逻辑回归模型评估痴呆症与地理位置偏远之间的关联。

结果

结果显示,从 2015 年到 2018 年,65 岁及以上成年人的痴呆症患病率在 2018 年(每 10 万人 5229 例)高于 2015 年(每 10 万人 5099 例)。澳大利亚成年人的痴呆症患病率存在显著的地理差异,而且这一趋势似乎在增加。此外,未调整模型显示,2015 年,居住在主要城市的老年人患痴呆症的几率是居住在外区域和偏远地区的老年人的 1.29 倍(优势比:1.29,95%置信区间:1.17-1.41)。2018 年,调整后的模型发现,居住在主要城市的老年人患痴呆症的几率比居住在外区域和偏远地区的同龄人高 1.12 倍(优势比:1.12,95%置信区间:1.01-1.25)。

结论

澳大利亚的痴呆症患病率呈上升趋势。需要进一步研究以确定这种增加的原因。增加公共卫生措施应集中于行为特征和环境因素,以改善这一趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f688/10395934/ce96e49432b3/pone.0289505.g001.jpg

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