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新西兰奥特亚罗瓦 2010-2019 年儿童癌症发病率和生存率。

Childhood cancer incidence & survival in Aotearoa, New Zealand 2010-2019.

机构信息

National Child Cancer Network, Aotearoa, New Zealand.

Starship Blood & Cancer Centre, Te Toka Tumai, Auckland, Aotearoa, New Zealand.

出版信息

Cancer Epidemiol. 2023 Oct;86:102433. doi: 10.1016/j.canep.2023.102433. Epub 2023 Jul 31.

Abstract

OBJECTIVE

To provide updated estimates of childhood cancer incidence and survival in Aotearoa, New Zealand.

METHOD

Registrations for children under the age of 15 years diagnosed with cancer between 2010 and 2019 were extracted from the New Zealand Children's Cancer Registry. Cases were stratified by age, sex, prioritised ethnicity (Māori, Pacific peoples, and non-Māori) and cancer type. Age-standardised incidence rates (ASRs) per million person years and observed survival rates were calculated.

RESULTS

During the study period, 1522 children were diagnosed with cancer providing an ASR of 169.1 per million per year (95 % Confidence Interval, CI: 157.0-181.2). For all childhood cancers combined, survival at 5-years was 85.6 % (95 % CI 83.7-87.3). There was a gap in 5-year survival between Māori (80.9 %, 95 % CI 76.5-84.6), Pacific peoples (82.6 %, 95 % CI 75.6-87,7) and Non-Māori (87.8 %, 95 % CI 85.6-89.7) In both adjusted and unadjusted models, this difference in survival was most marked (p < 0.05) among children who were 10-14 years of age at diagnosis.

CONCLUSION

Childhood cancer incidence and survival rates in Aotearoa, New Zealand remain comparable to other high-income countries. Further research is required to understand the survival difference between ethnic groups.

摘要

目的

提供新西兰奥塔哥地区儿童癌症发病率和生存率的最新估计。

方法

从新西兰儿童癌症登记处提取 2010 年至 2019 年间诊断为癌症的 15 岁以下儿童的登记数据。病例按年龄、性别、优先族裔(毛利人、太平洋岛民和非毛利人)和癌症类型进行分层。计算每百万人口年的年龄标准化发病率(ASR)和观察生存率。

结果

在研究期间,1522 名儿童被诊断患有癌症,ASR 为每年每百万人口 169.1 例(95%置信区间,CI:157.0-181.2)。所有儿童癌症综合来看,5 年生存率为 85.6%(95%CI 83.7-87.3)。毛利人(80.9%,95%CI 76.5-84.6)、太平洋岛民(82.6%,95%CI 75.6-87.7)和非毛利人(87.8%,95%CI 85.6-89.7)之间的 5 年生存率存在差距。在调整和未调整模型中,诊断时年龄为 10-14 岁的儿童之间的生存差异最为明显(p<0.05)。

结论

新西兰奥塔哥地区的儿童癌症发病率和生存率与其他高收入国家相当。需要进一步研究以了解不同族裔之间的生存差异。

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