Gavrish A S
Arkh Anat Gistol Embriol. 1986 Jun;90(6):13-21.
Morphofunctional peculiarities of various elements of the microhemocirculatory bed (MHCB) of the myocardium performing correction of the nutritive blood stream, structures and mechanisms of the microvessel permeability have been studied. The investigation has been performed on 20 mature rabbits and 5 mongrel dogs, transmissive electron microscopy and certain cytochemical techniques applied for revealing ATP-ase, lactate-, malate-, succinate-dehydrogenases, cytochrome-C-reductase and glycosamine glycans. Structural differences in microvessels of various range are described. Together with smooth muscle cells in arterioles and precapillary sphincters, specialized endotheliocytes and valve-like formations, situating in the orifices of blood capillaries, participate in regulation of hemoperfusion of the MHCB functional units. The data have been obtained characterising cytolemma of the endotheliocytes as a complex system, where plasmolemma, being the bearer of ATP-ase and a complex of oxidoreductase, regulates physical-chemical properties of the paraplasmolemmal layer and ensures the control of all the forms of the transcapillary transport. Micropinocytic vesicles are proved to differentiate into two functionally asynonymous populations: one of them performs the energy-dependent transport, while the other reserves the plasmolemma.
对心肌微血流循环床(MHCB)中执行营养血流校正功能的各个元素的形态功能特性、微血管通透性的结构和机制进行了研究。研究对象为20只成年兔和5只杂种犬,采用透射电子显微镜及某些细胞化学技术来揭示ATP酶、乳酸脱氢酶、苹果酸脱氢酶、琥珀酸脱氢酶、细胞色素C还原酶和糖胺聚糖。描述了不同管径微血管的结构差异。除了小动脉和毛细血管前括约肌中的平滑肌细胞外,位于毛细血管口的特殊内皮细胞和瓣膜样结构也参与了MHCB功能单位血流灌注的调节。已获得的数据表明内皮细胞的细胞膜是一个复杂的系统,其中质膜作为ATP酶和氧化还原酶复合物的载体,调节质膜旁层的物理化学性质,并确保对所有形式的跨毛细血管运输进行控制。微吞饮小泡被证明可分化为两个功能不同的群体:其中一个群体执行能量依赖性运输,而另一个群体则保留质膜。